Rams vs. Cardinals Prediction: NFL Week 17 Odds, Betting Picks

Los Angeles Rams head coach Sean McVay walks on the field during the NFL football team's organized team activities Tuesday, May 23, 2023, in Thousand Oaks, Calif.
(AP Photo/Marcio Jose Sanchez)
  • The Rams are a 6-point home favorite against the Cardinals.
  • The Cardinals have lost eight straight games after coming off overtime.
  • My Rams vs. Cardinals prediction is to use the Rams in a teaser.

Seeking their fifth straight win in pursuit of the division title, the Rams welcome the Cardinals to Los Angeles.ย 

LA earned its fourth straight win and cover with a 19-9 victory over the New York Jets on Sunday. After starting the season 1-4, the Rams have finished 8-2 in their last 10.ย 

Arizona fell 36-30 as road favorites in Carolina and is officially eliminated from playoff contention. A loss on Saturday would mark Arizonaโ€™s fourth straight road defeat.ย 

Bet on Rams vs. Cardinals and other NFL matchups with up-to-date NFL odds.ย 

NFL Week 17 Odds: Rams vs. Cardinals

Dec 28 - 6 pm EST

Cardinals at Rams

Rams vs. Cardinals Prediction

Based on Arizonaโ€™s poor record following an overtime game and the revenge spot for Los Angeles, my Rams vs. Cardinals prediction is to Tease Los Angeles (PK).ย 

This game is essentially the inverse of a Week 2 meeting between these NFC West foes.ย 

The Rams played an overtime game in Week 1 against Detroit and operated without Puka Nacua against Arizona.ย 

A 41-10 blowout win for Arizona shouldnโ€™t come as a surprise based on those facts.ย 

However, now itโ€™s Arizona off an overtime win without a key skill player. James Conner sustained a knee injury on Sunday and appears unlikely to play on Saturday night.ย 

Even worse news for the Cardinals is that theyโ€™re running into Sean McVay, who is 28-14 in game 12 onward in his career, including 9-1 in his last 10 contests.ย 

Plus, divisional favorites that lost by 31 or more points in the previous head-to-head meeting are 12-3 SU since 2003.ย 

Irrespective of those trends, the Rams excel this season when their offense shines.ย 

This season, Los Angeles is a perfect 6-0 SU when they score at least 21 points.ย 

Maybe itโ€™s an oversimplification, but the Cardinals have kept only one team under 21 points away from home this season.ย 

Coming off a game where they allowed 30 points in regulation to the Panthers, which sits 18 spots behind the Rams in offensive DVOA, Arizonaโ€™s defense faces an uphill climb.ย 

As a result, tease the Rams down through two key numbers and back them to win on Saturday.ย 

Betting Rams vs. Cardinals: NFL Public Betting

Check back on Friday for Rams vs. Cardinals public betting data and insights.ย 

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About the Author

Nick Hennion

Read More @nickhennion

Nick Hennion is a senior content writer for BetMGM. His previous stops include VSiN, NBC Sports, The Action Network and Forbes Betting. He owns a bachelor's degree from Syracuse University and a master's degree from Northwestern University.

Nick Hennion is a senior content writer for BetMGM. His previous stops include VSiN, NBC Sports, The Action Network and Forbes Betting. He owns a bachelor's degree from Syracuse University and a master's degree from Northwestern University.