Twins vs Guardians Prediction, Odds & Player Prop Bets Today – MLB, Sep 18

Cleveland Guardians' Josh Naylor runs the base path during a spring training baseball game against the San Diego Padres, Monday, Feb. 26, 2024, in Peoria, Ariz.
(AP Photo/Lindsey Wasson)
  • The Twins are +100 favorites vs the Guardians
  • Twins vs Guardians Over / Under today: 7.5 Runs
  • Twins / Guardians TV Channel: BSGL | BSNO

The Minnesota Twins (+100) visit Progressive Field to take on the Cleveland Guardians (-120) on Wednesday, September 18, 2024. First pitch is scheduled for 6:40pm EDT in Cleveland, OH.

This season, the Twins are 80-71 against the spread (ATS), while the Guardians are 77-75 ATS.

Twins vs Guardians Starting Pitchers Today:

  • Twins starting pitcher: Bailey Ober 12-7, 3.90 ERA
  • Guardians starting pitcher: Tanner Bibee 11-8, 3.63 ERA

Twins vs. Guardians Odds, Run Line, Over/Under & Moneyline

SpreadOver / UnderMoneyline
Twins+1.5 -250O 7.5 -125+100
Guardians -1.5 +175U 7.5 +105-120

Twins vs Guardians Prediction for Today’s Game

Based on recent trends the model predicts the Twins will win Wednesday‘s MLB game with 51.2% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.


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We’ve highlighted some favorite MLB player prop bets for Twins players for Wednesday‘s game, looking at profitable historical betting trends:

Best Twins Player Prop Bets Today:

  • Kyle Farmer has hit the Home Runs Over in 2 of his last 4 games (+12.60 Units / 315% ROI)
  • Royce Lewis has hit the Runs Under in 16 of his last 19 games (+11.60 Units / 43% ROI)
  • Jose Miranda has hit the RBIs Under in 13 of his last 14 away games (+11.05 Units / 36% ROI)
  • Royce Lewis has hit the Total Bases Under in 12 of his last 14 away games (+10.05 Units / 49% ROI)
  • Bailey Ober has hit the Pitching Outs Over in 10 of his last 11 games (+9.50 Units / 51% ROI)

And here are some favorite MLB player prop bets for Guardians players for Wednesday‘s game, looking at profitable historical betting trends:

Best Guardians Player Prop Best Bets Today:

  • Lane Thomas has hit the Home Runs Over in 5 of his last 14 games (+18.60 Units / 133% ROI)
  • Jose Ramirez has hit the RBIs Under in 17 of his last 20 games (+11.80 Units / 34% ROI)
  • Andres Gimenez has hit the Hits Under in 21 of his last 36 games (+10.30 Units / 19% ROI)
  • Angel Martinez has hit the Total Bases Over in 21 of his last 32 games (+10.25 Units / 22% ROI)
  • Bo Naylor has hit the Hits Runs and RBIs Under in 9 of his last 10 games (+8.75 Units / 72% ROI)
  • The Minnesota Twins have hit the Game Total Over in 48 of their last 85 games (+13.10 Units / 14% ROI)
  • The Minnesota Twins have hit the 1st Five Innings (F5) Team Total Under in 14 of their last 20 games (+8.45 Units / 36% ROI)
  • The Minnesota Twins have hit the 1st Five Innings (F5) Moneyline in 14 of their last 25 away games (+3.15 Units / 10% ROI)
  • The Minnesota Twins have covered the 1st Five Innings (F5) Run Line in 8 of their last 13 away games (+2.70 Units / 18% ROI)
  • The Minnesota Twins have covered the Run Line in 4 of their last 7 games (+1.05 Units / 13% ROI)
  • The Cleveland Guardians have hit the Game Total Under in 36 of their last 60 games (+13.90 Units / 21% ROI)
  • The Cleveland Guardians have hit the Moneyline in 87 of their last 152 games (+10.82 Units / 5% ROI)
  • The Cleveland Guardians have covered the Run Line in 35 of their last 70 games at home (+10.75 Units / 14% ROI)
  • The Cleveland Guardians have hit the 1st Five Innings (F5) Team Total Under in their last 5 games (+5.00 Units / 70% ROI)

Twins Against the Spread (ATS) Record

Against the spread this season, the Twins are 69-82 against the Run Line (-17.4 Units / -9.1% ROI).

  • 80-71 when betting on the Moneyline for -10.1 Units / -4.69% ROI
  • 76-66 when betting on the total runs Over for +3.7 Units / 2.24% ROI
  • 66-76 when betting on the total runs Under for -17.85 Units / -10.8% ROI

Guardians Against the Spread (ATS) Record

Against the spread this season, the Guardians are 77-75 against the Run Line (+4.45 Units / 2.34% ROI).

  • 87-65 when betting on the Moneyline for +10.82 Units / 5.49% ROI
  • 67-75 when betting on the total runs Over for -15.95 Units / -9.49% ROI
  • 75-67 when betting on the total runs Under for +1.35 Units / 0.81% ROI

Guardians vs Twins Home Run Prop Bets Today

Over Under
Byron Buxton (MIN) 0.5 +260 0.5 -350
Matt Wallner (MIN) 0.5 +310 0.5 -400
Royce Lewis (MIN) 0.5 +375 0.5 -500
Carlos Santana (MIN) 0.5 +450 0.5 -650
Jose Ramirez (CLE) 0.5 +450 0.5 -650

Guardians vs Twins Total Hits Prop Bets Today

Over Under
Andres Gimenez (CLE) 0.5 -225 0.5 +175
Jose Ramirez (CLE) 0.5 -225 0.5 +165
Byron Buxton (MIN) 0.5 -210 0.5 +155
Carlos Correa (MIN) 0.5 -210 0.5 +155
Royce Lewis (MIN) 0.5 -200 0.5 +150

Guardians vs Twins RBI Prop Bets Today

Over Under
Byron Buxton (MIN) 0.5 +150 0.5 -200
Josh Naylor (CLE) 0.5 +160 0.5 -225
Jose Ramirez (CLE) 0.5 +160 0.5 -210
Royce Lewis (MIN) 0.5 +165 0.5 -225
Matt Wallner (MIN) 0.5 +170 0.5 -225

Guardians vs Twins Strikeout Prop Bets Today

Over Under
Tanner Bibee (CLE) 6.5 -125 6.5 -105
Bailey Ober (MIN) 5.5 +130 5.5 -175

Opponents are hitting just .125 (31-for-248) against Bailey Ober’s non-fastballs this season — best among qualified SPs in MLB; League Avg: .217 — 100th Percentile.

Opponents have a groundball batting average of .419 (26 GB hits out of 62 GBs) against Bailey Ober with runners in scoring position since the 2022 season — highest in MLB among starting pitchers with at least 189 total IP; League Avg: .237 — 0 Percentile.

Opponents have a groundball rate of just 34% (144/425) against Bailey Ober this season — 2nd lowest among qualified SPs in MLB; League Avg: 44% — third Percentile.

Opponents have a groundball rate of just 33% (49/150) against Bailey Ober in two-strike counts this season — lowest among qualified SPs in MLB; League Avg: 45% — first Percentile.

Guardians Starting Pitcher Stats & Trends

Opponents had a groundball rate of just 12% (2/16) against Tanner Bibee in his last start — tied for lowest in MLB over the last week; League Avg: 43% — second Percentile.

Opponents have a groundball rate of just 28% (72/257) against Tanner Bibee in non-two strike counts this season — lowest among qualified SPs in MLB; League Avg: 42% — first Percentile.

Opponents have a groundball rate of just 34% (148/435) against Tanner Bibee this season — 3rd lowest among qualified SPs in MLB; League Avg: 44% — fifth Percentile.

Tanner Bibee has a strikeout rate of 30% (79 SO in 261 PAs) when going through the lineup the first time in a game this season — 8th best among qualified SPs in MLB; League Avg: 25% — 87th Percentile.

Twins Keys to the Game vs. the Guardians

The Twins are just 26-36 (.419) when tied entering the 7th inning since the 2022 season — 3rd lowest in MLB; League Avg: .500.

The Twins are 26-103 (.202) when trailing entering the 7th inning since the 2023 season — tied for 2nd best in MLB; League Avg: .142.

The Twins are 206-5 (.976) when leading entering the 9th inning since the 2022 season — 2nd best in MLB; League Avg: .950.

The Twins are 138-2 (.986) when leading entering the 9th inning since the 2023 season — best in MLB; League Avg: .949.

Guardians Keys to the Game vs. the Twins

The Guardians are 24-29 (.453) when allowing 2 or more home runs this season — best in MLB; League Avg: .294.

The Guardians are 73-2 (.973) when leading entering the 8th inning this season — best in MLB; League Avg: .899.

The Guardians are 14-6 (.700) when tied entering the 7th inning this season — 2nd best in MLB; League Avg: .500.

The Guardians are just 9-16 (.360) after a loss as underdogs this season — 4th lowest in MLB; League Avg: .434.

The Twins are batting just .200 in lefty-lefty matchups since last season — lowest in MLB; League Avg: .239.

Twins hitters have an OPS of .750 (8,870 PA’s) against RHP since last season — 5th best in MLB; League Avg: .723.

The Twins are batting just .160 with two-strikes since last season — tied for 5th lowest in MLB; League Avg: .170.

Twins hitters have an OBP of .324 (13,262 PA’s) against RHP since the 2022 season — tied for 2nd best in MLB; League Avg: .314.

Guardians hitters have put just 34% of balls in play to the left side of the field with runners in scoring position since the 2022 season — lowest in MLB; League Avg: 38%.

Guardians hitters have a Hard-Hit Rate of just 34% on the first pitch of at-bats this season — lowest in MLB; League Avg: 42%.

Guardians hitters have a Hard-Hit Rate of just 34% this season — lowest in MLB; League Avg: 39%.

The Guardians had an average Exit Velocity of 87.5 MPH in the 2023 season — lowest in MLB; League Avg: 89.0.

Twins pitchers have walked 391 of 5,603 batters (7%) this season — tied for 2nd best in MLB; League Avg: 8%.

Twins pitchers have a strikeout rate of 45% with two-strikes since last season — 2nd best in MLB; League Avg: 42%.

Opponents have a groundball rate of just 41% against Twins pitchers since the 2022 season — tied for 3rd lowest in MLB; League Avg: 43%.

Twins pitchers have walked 182 of 2,795 batters (7%) when facing the leadoff batter in the inning since last season — 3rd best in MLB; League Avg: 8%.

Opponents have a groundball batting average of just .222 against Guardians pitchers this season — best in MLB; League Avg: .249.

Opponents have a groundball batting average of just .204 against Guardians pitchers with runners on base this season — best in MLB; League Avg: .262.

Guardians pitchers have allowed a run just 12% of the time after an opposing score this month (16 games) — lowest in MLB; League Avg: 29%.

The Guardians have allowed 0.88 runs per game (133/152) in late innings this season — best in MLB; League Avg: 1.30.

Guardians vs. Twins Injuries Tonight That May Affect Prop Bets 

  • Cleveland Guardians – No Injuries Reported
  • Minnesota Twins – No Injuries Reported

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About the Author

Shane Jackson

Read More @Sjacksonmgm

Shane Jackson is a Web Content Writer for BetMGM, covering MLB and NBA. After graduating from the University of Kansas, his previous stops include MLB.com, Lawrence Journal-World, Manhattan Mercury, Bet Chicago Sports, WynnBET, and Sportsbook Review.

Shane Jackson is a Web Content Writer for BetMGM, covering MLB and NBA. After graduating from the University of Kansas, his previous stops include MLB.com, Lawrence Journal-World, Manhattan Mercury, Bet Chicago Sports, WynnBET, and Sportsbook Review.