Twins vs Nationals Prediction, Odds & Player Prop Bets Today – MLB, May 22

Washington Nationals designated hitter Joey Meneses (45) bats during a baseball game against the Detroit Tigers at Nationals Park, Sunday, May 21, 2023, in Washington.
(AP Photo/Alex Brandon)
  • The Twins are -185 favorites vs the Nationals
  • Twins vs Nationals Over / Under today: 8.5 Runs
  • Twins / Nationals TV Channel: BSNO | MASN

The Minnesota Twins () visit Nationals Park to take on the Washington Nationals () on Wednesday, May 22, 2024. First pitch is scheduled for 1:05pm EDT in Washington, DC.

This season, the Twins are 25-23 against the spread (ATS), while the Nationals are 28-19 ATS.

Twins vs Nationals Starting Pitchers Today:

  • Twins starting pitcher: Simeon Woods Richardson 1-0, 3.00 ERA
  • Nationals starting pitcher: Jake Irvin 2-4, 3.91 ERA

Twins vs. Nationals Odds, Run Line, Over/Under & Moneyline

SpreadOver / UnderMoneyline
Twins O
Nationals U

Twins vs Nationals Prediction for Today’s Game

Based on recent trends the model predicts the Twins will win Wednesday‘s MLB game with 56.2% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.


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We’ve highlighted some favorite MLB player prop bets for Twins players for Wednesday‘s game, looking at profitable historical betting trends:

Best Twins Player Prop Bets Today:

  • Carlos Santana has hit the Home Runs Over in 6 of his last 14 away games (+25.70 Units / 184% ROI)
  • Alex Kirilloff has hit the Hits Under in 15 of his last 19 games (+16.10 Units / 61% ROI)
  • Alex Kirilloff has hit the Total Bases Under in 16 of his last 19 games (+14.35 Units / 57% ROI)
  • Alex Kirilloff has hit the Singles Under in 22 of his last 29 games (+14.35 Units / 41% ROI)
  • Christian Vazquez has hit the Hits Runs and RBIs Under in 16 of his last 20 games (+11.30 Units / 40% ROI)

And here are some favorite MLB player prop bets for Nationals players for Wednesday‘s game, looking at profitable historical betting trends:

Best Nationals Player Prop Best Bets Today:

  • Eddie Rosario has hit the Home Runs Over in 5 of his last 12 games (+26.30 Units / 219% ROI)
  • Luis Garcia has hit the Runs Under in 21 of his last 24 games (+15.35 Units / 35% ROI)
  • Jesse Winker has hit the Singles Under in 15 of his last 17 games (+11.75 Units / 42% ROI)
  • Joey Meneses has hit the RBIs Over in 8 of his last 12 games at home (+11.20 Units / 93% ROI)
  • Luis Garcia has hit the Hits Under in 14 of his last 18 games (+11.15 Units / 33% ROI)
  • The Minnesota Twins have hit the 1st Five Innings (F5) Team Total Under in 14 of their last 20 games (+7.59 Units / 31% ROI)
  • The Minnesota Twins have hit the Moneyline in 18 of their last 28 games (+5.10 Units / 12% ROI)
  • The Minnesota Twins have hit the Team Total Over in 19 of their last 31 games (+4.70 Units / 13% ROI)
  • The Minnesota Twins have covered the Run Line in 15 of their last 26 games (+4.40 Units / 13% ROI)
  • The Minnesota Twins have hit the Game Total Over in 10 of their last 17 away games (+3.45 Units / 18% ROI)
  • The Washington Nationals have covered the Run Line in 25 of their last 39 games (+10.55 Units / 21% ROI)
  • The Washington Nationals have hit the Moneyline in 19 of their last 39 games (+9.05 Units / 23% ROI)
  • The Washington Nationals have hit the 1st Five Innings (F5) Moneyline in 18 of their last 39 games (+7.45 Units / 19% ROI)
  • The Washington Nationals have hit the Game Total Under in 23 of their last 41 games (+6.30 Units / 14% ROI)
  • The Washington Nationals have hit the 1st Five Innings (F5) Team Total Under in 8 of their last 10 games at home (+5.45 Units / 45% ROI)

Twins Against the Spread (ATS) Record

Against the spread this season, the Twins are 24-24 against the Run Line (-2.2 Units / -3.46% ROI).

  • 25-23 when betting on the Moneyline for -3.85 Units / -6.05% ROI
  • 23-22 when betting on the total runs Over for -1.15 Units / -2.22% ROI
  • 22-23 when betting on the total runs Under for -3.3 Units / -6.4% ROI

Nationals Against the Spread (ATS) Record

Against the spread this season, the Nationals are 28-19 against the Run Line (+6.63 Units / 10.96% ROI).

  • 21-26 when betting on the Moneyline for +5.8 Units / 12.12% ROI
  • 20-24 when betting on the total runs Over for -6.25 Units / -12.18% ROI
  • 24-20 when betting on the total runs Under for +1.78 Units / 3.42% ROI

Nationals vs Twins Home Run Prop Bets Today

Over Under
Ryan Jeffers (MIN) 0.5 +290 0.5 -375
Byron Buxton (MIN) 0.5 +300 0.5 -400
Joey Gallo (WAS) 0.5 +375 0.5 -500
CJ Abrams (WAS) 0.5 +450 0.5 -650
Eddie Rosario (WAS) 0.5 +450 0.5 -650

Nationals vs Twins Total Hits Prop Bets Today

Over Under
Luis Garcia (WAS) 0.5 -275 0.5 +195
Joey Meneses (WAS) 0.5 -250 0.5 +190
CJ Abrams (WAS) 0.5 -250 0.5 +180
Willi Castro (MIN) 0.5 -250 0.5 +190
Byron Buxton (MIN) 0.5 -225 0.5 +170

Nationals vs Twins RBI Prop Bets Today

Over Under
Jose Miranda (MIN) 0.5 +115 0.5 -150
Byron Buxton (MIN) 0.5 +120 0.5 -155
Ryan Jeffers (MIN) 0.5 +140 0.5 -190
Carlos Correa (MIN) 0.5 +145 0.5 -190
Joey Meneses (WAS) 0.5 +170 0.5 -225

Nationals vs Twins Strikeout Prop Bets Today

Over Under
Patrick Corbin (WAS) 3.5 +105 3.5 -135
Joe Ryan (MIN) 6.5 +125 6.5 -160

Opponents have a groundball rate of just 29% (13/44) against Simeon Woods Richardson in two-strike counts this season — tied for 5th lowest in MLB among starting pitchers with at least 18 total IP; League Avg: 45% — fourth Percentile.

Simeon Woods Richardson has allowed a slugging percentage of .750 (15 Total Bases / 20 ABs) on changeups this season — 2nd highest in MLB among starting pitchers with at least 18 total IP; League Avg: .357 — second Percentile.

Opponents have a miss rate of just 14% (8/59) against Simeon Woods Richardson on changeups this season — lowest in MLB among starting pitchers with at least 18 total IP; League Avg: 30% — first Percentile.

Simeon Woods Richardson has not walked any of the 21 batters that he has faced over the past seven days (1 games) — tied for best among AL Starters over the last week; League Avg: 6% — 100th Percentile.

Nationals Starting Pitcher Stats & Trends

Jake Irvin has a strikeout rate of just 11% (9 SO in 81 PAs) when going through the lineup the second time in a game this season — lowest among among NL Starters; League Avg: 22% — second Percentile.

Jake Irvin has walked 1 of 95 right-handed batters (1%) this season — 2nd best among qualified SPs in MLB; League Avg: 7% — 98th Percentile.

Jake Irvin’s K:BB ratio is 18.0 (18/1) against right-handed batters this season — tied for best among qualified SPs in MLB; League Avg: 3.4 — 100th Percentile.

Jake Irvin has walked 9 of 207 batters (4%) this season — tied for 3rd best among among NL Starters; League Avg: 8% — 95th Percentile.

Twins Keys to the Game vs. the Nationals

The Twins are just 17-30 (.362) when tied entering the 7th inning since the 2022 season — lowest in MLB; League Avg: .500.

The Twins are 15-80 (.158) when trailing entering the 8th inning since the 2023 season — 2nd best in MLB; League Avg: .102.

The Twins are 21-68 (.236) when trailing entering the 7th inning since the 2023 season — 2nd best in MLB; League Avg: .144.

The Twins are 91-1 (.989) when leading entering the 9th inning since the 2023 season — best in MLB; League Avg: .947.

Nationals Keys to the Game vs. the Twins

The Nationals are 5-1 (.833) after a loss as favorites since the 2023 season — best in MLB; League Avg: .574.

The Nationals are just 53-93 (.363) after a win since the 2022 season — lowest in MLB; League Avg: .512.

The Nationals are just 23-43 (.348) after a home win since the 2022 season — lowest in MLB; League Avg: .534.

The Nationals are just 140-194 (.419) when allowing 5 or more extra base hits since the 2022 season — 2nd lowest in MLB; League Avg: .535.

Twins hitters have drawn 26 walks in 459 PA’s (6%) against LHP this season — lowest in MLB; League Avg: 8%.

Twins hitters are slugging .445 against LHP this season — 4th best in MLB; League Avg: .387.

The Twins are batting just .153 with two-strikes since last season — tied for lowest in MLB; League Avg: .171.

The Twins are batting .275 against LHP this season — tied for 4th best in MLB; League Avg: .244.

The Nationals are batting just .104 on pitches out of the zone this season — lowest in MLB; League Avg: .155.

The Nationals are batting just .131 when facing the starting pitcher for the 3rd time in a game over the last 14 days — lowest in MLB; League Avg: .278.

Nationals hitters are slugging just .411 when facing the starting pitcher for the 3rd time in a game since the 2022 season — tied for 2nd lowest in MLB; League Avg: .447.

Nationals hitters have put 40% of their swings in play against LHP since last season — highest in MLB; League Avg: 37%.

Twins pitchers have walked 121 of 1,788 batters (7%) this season — tied for best in MLB; League Avg: 8%.

Twins pitchers have a strikeout rate of 28% versus the bottom of the order this season — best in MLB; League Avg: 24%.

Opponents have a groundball rate of just 36% against Twins pitchers this month (19 games) — lowest in MLB; League Avg: 43%.

Opponents have a groundball rate of just 38% against Twins pitchers this season — 3rd lowest in MLB; League Avg: 43%.

Opponents have a miss rate of just 23% against Nationals pitchers since last season — 2nd lowest in MLB; League Avg: 26%.

Nationals pitchers have a strikeout rate of just 20% since the 2022 season — 2nd lowest in MLB; League Avg: 23%.

Nationals pitchers have walked 21 of 159 batters (13%) when facing the leadoff batter in the inning this month (18 games) — highest in MLB; League Avg: 7%.

Nationals pitchers have a strikeout rate of just 20% in late innings since last season — lowest in MLB; League Avg: 24%.

Nationals vs. Twins Injuries Tonight That May Affect Prop Bets 

  • Zach Brzykcy (Washington Nationals): Elbow, Out
  • Stone Garrett (Washington Nationals): Ankle, 10-Day IL
  • Stephen Strasburg (Washington Nationals): Shoulder, 60-Day IL
  • Nick Senzel (Washington Nationals): Thumb, 10-Day IL
  • Mason Thompson (Washington Nationals): Elbow, 60-Day IL
  • Cade Cavalli (Washington Nationals): Elbow, 60-Day IL
  • Zack Weiss (Minnesota Twins): Shoulder, 15-Day IL
  • Jhoan Duran (Minnesota Twins): Oblique, 15-Day IL
  • Anthony DeSclafani (Minnesota Twins): Elbow, 60-Day IL
  • Matt Canterino (Minnesota Twins): Shoulder, 7-Day IL
  • Trevor Larnach (Minnesota Twins): Toe, 7-Day IL
  • Royce Lewis (Minnesota Twins): Quadriceps, 10-Day IL
  • Max Kepler (Minnesota Twins): Leg, Day-To-Day
  • Jovani Moran (Minnesota Twins): Elbow, 60-Day IL
  • Josh Staumont (Minnesota Twins): Calf, 15-Day IL
  • Caleb Thielbar (Minnesota Twins): Hamstring, 15-Day IL
  • Justin Topa (Minnesota Twins): Kneecap, 15-Day IL
  • Jose De Leon (Minnesota Twins): Elbow, Out
  • Josh Winder (Minnesota Twins): Shoulder, 60-Day IL

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About the Author

Shane Jackson

Read More @Sjacksonmgm

Shane Jackson is a Web Content Writer for BetMGM, covering MLB and NBA. After graduating from the University of Kansas, his previous stops include MLB.com, Lawrence Journal-World, Manhattan Mercury, Bet Chicago Sports, WynnBET, and Sportsbook Review.

Shane Jackson is a Web Content Writer for BetMGM, covering MLB and NBA. After graduating from the University of Kansas, his previous stops include MLB.com, Lawrence Journal-World, Manhattan Mercury, Bet Chicago Sports, WynnBET, and Sportsbook Review.