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The Niners odds to win the Super Bowl are off the board.
The Niners odds to win the NFC Championship are off the board.
The Niners odds to win the NFC West are off the board.
Brandon Aiyuk is entering the final year of his rookie contract. Read More
The Arizona Cardinals (1-3-0) visit Levi’s Stadium to take on the San Francisco 49ers (2-2-0) on Oct. 6. Kickoff is scheduled for 4:05pm EDT in Santa Clara, CA. The 49ers are betting favorites i Read More
Check out NFL odds and predictions, along with my NFC West Predictions, for the 2024 division winner market. Read More
The New England Patriots (1-2-0) visit Levi’s Stadium to take on the San Francisco 49ers (1-2-0) on Sep. 29. Kickoff is scheduled for 4:05pm EDT in Santa Clara, CA. The 49ers are betting favorit Read More
Get the latest 2024 49ers over under wins for their NFL season win total, along with win total predictions and live win total odds. Read More
Read about the QBs taken after the 49ers drafted Trey Lance at third overall in the 2021 NFL Draft. Read More
Get my Rams vs. 49ers prediction based on NFL odds at the BetMGM online sportsbook for Week 3’s NFC West matchup. Read More
The San Francisco 49ers (1-1-0) visit SoFi Stadium to take on the Los Angeles Rams (0-2-0) on Sep. 22. Kickoff is scheduled for 4:25pm EDT in Inglewood, CA. The 49ers are betting favorites in this mat Read More
Read about the youngest players currently on the Niners’ roster. Read More
You can bet on spread, moneylines, over/under totals, parlays, and more San Francisco 49ers odds each season.
If you’re in San Francisco and interested in odds for other teams, check out:
Will the 49ers win the NFC West? Will they win the Super Bowl? How many interceptions will a certain player have this year?
For example: If you bet $20 on the 49ers (+200) to win the division, the bet would settle when the 49ers are eliminated or when they clinch the division.
What’s the final scoring margin of the 49ers’ game?
For example: If you bet $200 on the 49ers -3.5 (-115) against the Carolina Panthers, San Francisco must win the game by at least four points.
Alternatively, if you bet $200 on the 49ers +4.5 (-110) against the Philadelphia Eagles, San Francisco must lose by four or fewer points (or win the game).
If the scoring margin is identical to the spread (e.g., -2 or +7), the bet is a push, and your money is refunded.
Will the 49ers win the matchup?
For example: If you bet $50 on the 49ers -200 against the Miami Dolphins, San Francisco must win the game (in regulation or overtime).
If the game ends in a tie, the bet is a push.
What is the number of points scored by both teams in the game?
For example: If you bet $15 on over 49.5 (-110) in their game against the Detroit Lions, the teams must combine for at least 50 points.
Alternatively, if you bet $25 on under 29.5 (-110), the teams must combine for 29 or fewer points.
If the combined point total is identical to the over/under total, the bet is a push.
You can combine 49ers’ bets and other NFL bets into one parlay.
For example: If you bet $10 on a three-leg parlay with the 49ers’ moneyline (+110) vs. the Buffalo Bills, Falcons’ moneyline (-125 vs. the Las Vegas Raiders), and over 49.5 (-115) in the Pittsburgh Steelers-Cincinnati Bengals game, all three legs must hit for the bet to cash.
If one bet is a push, it’s eliminated from the parlay, and odds (and payout) are recalculated without that leg.
Read the latest betting tips and how-to guides from BetMGM experts.
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