Brewers vs Cardinals Prediction, Odds & Player Prop Bets Today – MLB, Aug 21

St. Louis Cardinals' Jordan Walker warms up before a baseball game against the Milwaukee Brewers Thursday, Sept. 28, 2023, in Milwaukee. (AP Photo/Aaron Gash)
(AP Photo/Aaron Gash)
  • The Brewers are -110 favorites vs the Cardinals
  • Brewers vs Cardinals Over / Under today: 7.5 Runs
  • Brewers / Cardinals TV Channel: FS1 | BSWI | BSMW

The Milwaukee Brewers (-110) visit Busch Stadium to take on the St. Louis Cardinals (-110) on Wednesday, August 21, 2024. First pitch is scheduled for 7:45pm EDT in St. Louis, MO.

This season, the Brewers are 73-52 against the spread (ATS), while the Cardinals are 61-64 ATS.

Brewers vs Cardinals Starting Pitchers Today:

  • Brewers starting pitcher: Tobias Myers 6-5, 2.81 ERA
  • Cardinals starting pitcher: Kyle Gibson 7-5, 4.25 ERA

Brewers vs. Cardinals Odds, Run Line, Over/Under & Moneyline

SpreadOver / UnderMoneyline
Brewers-1.5 +155O 7.5 -110-110
Cardinals +1.5 -190U 7.5 -110-110

Brewers vs Cardinals Prediction for Today’s Game

Based on recent trends the model predicts the Brewers will win Wednesday‘s MLB game with 51.3% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.


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We’ve highlighted some favorite MLB player prop bets for Brewers players for Wednesday‘s game, looking at profitable historical betting trends:

Best Brewers Player Prop Bets Today:

  • William Contreras has hit the Singles Under in 26 of his last 35 games (+17.65 Units / 46% ROI)
  • Jackson Chourio has hit the Total Bases Over in 27 of his last 42 games (+14.45 Units / 29% ROI)
  • Brice Turang has hit the Hits Under in 24 of his last 35 games (+14.35 Units / 24% ROI)
  • William Contreras has hit the Home Runs Over in 6 of his last 17 games (+14.30 Units / 84% ROI)
  • Jackson Chourio has hit the Runs Over in 25 of his last 44 games (+13.25 Units / 29% ROI)

And here are some favorite MLB player prop bets for Cardinals players for Wednesday‘s game, looking at profitable historical betting trends:

Best Cardinals Player Prop Best Bets Today:

  • Masyn Winn has hit the Home Runs Over in 5 of his last 16 games at home (+28.50 Units / 178% ROI)
  • Pedro Pages has hit the Singles Over in 19 of his last 26 games (+15.70 Units / 60% ROI)
  • Pedro Pages has hit the Hits Over in 20 of his last 24 games (+14.15 Units / 38% ROI)
  • Brendan Donovan has hit the Runs Under in 21 of his last 25 games (+13.70 Units / 28% ROI)
  • Pedro Pages has hit the Total Bases Over in 19 of his last 24 games (+12.00 Units / 33% ROI)
  • The Milwaukee Brewers have hit the Moneyline in 73 of their last 125 games (+14.50 Units / 9% ROI)
  • The Milwaukee Brewers have hit the Game Total Over in 66 of their last 121 games (+13.95 Units / 11% ROI)
  • The Milwaukee Brewers have covered the 1st Five Innings (F5) Run Line in 71 of their last 125 games (+11.10 Units / 8% ROI)
  • The Milwaukee Brewers have covered the Run Line in 53 of their last 97 games (+8.85 Units / 7% ROI)
  • The Milwaukee Brewers have hit the 1st Five Innings (F5) Moneyline in 5 of their last 6 games (+5.00 Units / 72% ROI)
  • The St. Louis Cardinals have hit the Game Total Over in 32 of their last 55 games (+6.30 Units / 10% ROI)
  • The St. Louis Cardinals have hit the 1st Five Innings (F5) Team Total Over in 8 of their last 11 games at home (+4.70 Units / 35% ROI)
  • The St. Louis Cardinals have covered the Run Line in 23 of their last 45 games at home (+3.05 Units / 5% ROI)

Brewers Against the Spread (ATS) Record

Against the spread this season, the Brewers are 66-59 against the Run Line (+3.6 Units / 2.17% ROI).

  • 73-52 when betting on the Moneyline for +14.5 Units / 9.21% ROI
  • 67-51 when betting on the total runs Over for +11.75 Units / 8.6% ROI
  • 51-67 when betting on the total runs Under for -22.85 Units / -16.5% ROI

Cardinals Against the Spread (ATS) Record

Against the spread this season, the Cardinals are 61-64 against the Run Line (-9 Units / -5.34% ROI).

  • 61-64 when betting on the Moneyline for -14.8 Units / -9.76% ROI
  • 59-61 when betting on the total runs Over for -8.5 Units / -6.23% ROI
  • 61-59 when betting on the total runs Under for -4.1 Units / -3% ROI

Cardinals vs Brewers Home Run Prop Bets Today

Over Under
Willson Contreras (STL) 0.5 +400 0.5 -550
Paul Goldschmidt (STL) 0.5 +425 0.5 -600
Rhys Hoskins (MIL) 0.5 +450 0.5 -650
William Contreras (MIL) 0.5 +500 0.5 -700
Willy Adames (MIL) 0.5 +500 0.5 -700

Cardinals vs Brewers Total Hits Prop Bets Today

Over Under
Masyn Winn (STL) 0.5 -275 0.5 +195
Jackson Chourio (MIL) 0.5 -250 0.5 +190
Brendan Donovan (STL) 0.5 -250 0.5 +175
William Contreras (MIL) 0.5 -225 0.5 +170
Nolan Arenado (STL) 0.5 -210 0.5 +160

Cardinals vs Brewers RBI Prop Bets Today

Over Under
William Contreras (MIL) 0.5 +140 0.5 -185
Jackson Chourio (MIL) 0.5 +165 0.5 -225
Willson Contreras (STL) 0.5 +165 0.5 -225
Willy Adames (MIL) 0.5 +165 0.5 -225
Nolan Arenado (STL) 0.5 +170 0.5 -225

Cardinals vs Brewers Strikeout Prop Bets Today

Over Under
Kyle Gibson (STL) 4.5 -165 4.5 +130
Tobias Myers (MIL) 4.5 +110 4.5 -145

Opponents are hitting just .155 (11-for-71) against Tobias Myers with runners in scoring position this season — 3rd best in MLB among starting pitchers with at least 50 total IP; League Avg: .251 — 98th Percentile.

Tobias Myers has walked 1 of 52 batters (2%) in his last two starts — 5th best in MLB over the last two weeks; League Avg: 7% — 96th Percentile.

Tobias Myers has a strikeout rate of just 4% (1 SO in 26 PAs) over the past seven days (1 games) — lowest among NL Starters over the last week; League Avg: 21% — second Percentile.

Tobias Myers has allowed an OPS of just .481 (80 PA’s) with runners in scoring position this season — 3rd best in MLB among starting pitchers with at least 50 total IP; League Avg: .731 — 98th Percentile.

Cardinals Starting Pitcher Stats & Trends

Kyle Gibson has walked 21 of 129 batters (16%) with runners in scoring position this season — highest among qualified SPs in MLB; League Avg: 8% — first Percentile.

Kyle Gibson has a strike rate of just 56% (275/493) with runners in scoring position this season — lowest among qualified SPs in MLB; League Avg: 64% — first Percentile.

Kyle Gibson has a strike rate of just 60% (1,291/2,137) this season — tied for 2nd lowest among qualified SPs in MLB; League Avg: 65% — fourth Percentile.

Kyle Gibson has a strike rate of just 58% (659/1,137) vs left-handed batters this season — lowest among qualified SPs in MLB; League Avg: 64% — second Percentile.

Brewers Keys to the Game vs. the Cardinals

The Brewers are 34-74 (.315) when allowing 5 or more runs since the 2023 season — best in MLB; League Avg: .211.

The Brewers are 44-3 (.936) when they’ve had 5 or more XBH since the 2023 season — best in MLB; League Avg: .797.

The Brewers are 15-35 (.300) when allowing 5 or more runs this season — tied for best in MLB; League Avg: .199.

The Brewers are 48-119 (.287) when allowing 5 or more runs since the 2022 season — best in MLB; League Avg: .205.

Cardinals Keys to the Game vs. the Brewers

The Cardinals are just 23-37 (.383) after a win as favorites since the 2023 season — 3rd lowest in MLB; League Avg: .574.

The Cardinals are 34-18 (.654) when tied entering the 8th inning since the 2022 season — 2nd best in MLB; League Avg: .500.

The Cardinals are 52-1 (.981) when leading entering the 9th inning this season — tied for 4th best in MLB; League Avg: .946.

The Cardinals are 15-12 (.556) after a loss as underdogs this season — tied for 3rd best in MLB; League Avg: .436.

10% of Brewers’ hitters plate appearances have lasted only one pitch (1,629/16,968 PA’s) since the 2022 season — lowest in MLB; League Avg: 11%.

Brewers hitters have an OBP of .298 (363 PA’s) with two-strikes this month (17 games) — best in MLB; League Avg: .245.

Brewers hitters have an OBP of .332 (1,198 PA’s) against LHP this season — tied for 4th best in MLB; League Avg: .316.

Brewers hitters have chased 25% of pitches out of the zone against LHP this season — 2nd lowest in MLB; League Avg: 29%.

Cardinals hitters are slugging just .379 against LHP since last season — 2nd lowest in MLB; League Avg: .411.

Cardinals hitters have an OPS of just .653 (1,447 PA’s) against LHP this season — 5th lowest in MLB; League Avg: .718.

Cardinals hitters have an OPS of just .687 (3,007 PA’s) against LHP since last season — 2nd lowest in MLB; League Avg: .732.

Cardinals hitters have an OBP of just .294 (1,447 PA’s) against LHP this season — 4th lowest in MLB; League Avg: .316.

Opponents have a groundball rate of just 36% against Brewers pitchers over the last 14 days — 2nd lowest in MLB; League Avg: 42%.

Brewers pitchers allowed opponents to score in three different innings in 38% of their games in the 2023 season — lowest in MLB; League Avg: 49%.

Brewers pitchers have an ERA of 3.21 (820.2 IP) against division opponents since last season — 2nd best in MLB; League Avg: 4.23.

Brewers pitchers have an ERA of 3.73 (1250.2 IP) on the road since last season — best in MLB; League Avg: 4.35.

Opponents have a miss rate of just 23% against Cardinals pitchers since the 2022 season — 2nd lowest in MLB; League Avg: 26%.

Opponents have a miss rate of just 23% against Cardinals pitchers since last season — tied for 2nd lowest in MLB; League Avg: 26%.

Opponents have a groundball rate of 46% against Cardinals pitchers since the 2022 season — 2nd highest in MLB; League Avg: 43%.

Cardinals pitchers have walked 171 of 2,545 batters (7%) when facing the leadoff batter in the inning since last season — 4th best in MLB; League Avg: 8%.

Cardinals vs. Brewers Injuries Tonight That May Affect Prop Bets 

  • Keynan Middleton (St. Louis Cardinals): Forearm, 60-Day IL
  • Zack Thompson (St. Louis Cardinals): Undisclosed, 7-Day IL
  • Drew Rom (St. Louis Cardinals): Shoulder, 60-Day IL
  • Steven Matz (St. Louis Cardinals): Back, 60-Day IL
  • Riley O’Brien (St. Louis Cardinals): Forearm, 60-Day IL
  • Tommy Edman (St. Louis Cardinals): Wrist, 60-Day IL
  • J.C. Mejia (Milwaukee Brewers): Suspension, Suspension
  • Christian Arroyo (Milwaukee Brewers): Undisclosed, 7-Day IL
  • DL Hall (Milwaukee Brewers): Knee, 60-Day IL
  • Easton McGee (Milwaukee Brewers): Elbow, 60-Day IL
  • Wade Miley (Milwaukee Brewers): Elbow, 60-Day IL
  • Devin Williams (Milwaukee Brewers): Back, 60-Day IL
  • Joe Ross (Milwaukee Brewers): Back, 60-Day IL
  • Greg Allen (Milwaukee Brewers): Undisclosed, 7-Day IL
  • Brandon Woodruff (Milwaukee Brewers): Shoulder, 60-Day IL
  • J.B. Bukauskas (Milwaukee Brewers): Triceps, 60-Day IL
  • Abner Uribe (Milwaukee Brewers): Knee, 7-Day IL
  • Christian Yelich (Milwaukee Brewers): Back, 10-Day IL
  • Oliver Dunn (Milwaukee Brewers): Back, 60-Day IL

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About the Author

Shane Jackson

Read More @Sjacksonmgm

Shane Jackson is a Web Content Writer for BetMGM, covering MLB and NBA. After graduating from the University of Kansas, his previous stops include MLB.com, Lawrence Journal-World, Manhattan Mercury, Bet Chicago Sports, WynnBET, and Sportsbook Review.

Shane Jackson is a Web Content Writer for BetMGM, covering MLB and NBA. After graduating from the University of Kansas, his previous stops include MLB.com, Lawrence Journal-World, Manhattan Mercury, Bet Chicago Sports, WynnBET, and Sportsbook Review.