- The Brewers (82-72) are -160 favorites vs the Cardinals (90-65)
- Cardinals starting pitcher: José Quintana (6-6), 3.02 ERA
- Brewers starting pitcher: Brandon Woodruff (12-4), 3.18 ERA
- Watch the game on BSWI
The St. Louis Cardinals (+135) visit American Family Field to take on the Milwaukee Brewers (-160) on Wednesday, September 28, 2022. First pitch is scheduled for 7:40pm EDT in Milwaukee.
The Brewers are betting favorites in this MLB matchup, with the run line sitting at -1.5 (+135).
The Cardinals vs Brewers Over/Under is 7 total runs for the game.
So far this season, the Cardinals are 90-65 against the spread (ATS), while the Brewers are 65-88 ATS.
Cardinals vs. Brewers Odds, Run Line, Over/Under & Moneyline
| Spread | Over / Under | Moneyline | |
| Cardinals | +1.5 -160 | O 7 +100 | +135 |
| Brewers | -1.5 +135 | U 7 -120 | -160 |
Cardinals vs Brewers Prediction for Today’s Game
Based on recent trends the model predicts the Brewers will win Wednesday‘s matchup with 57.8% confidence.
This prediction factors in starting pitchers, recent team and player hitting performances, the last 5 games for both the Cardinals and Brewers and up-to-date player injuries.
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Best Cardinals Player Prop Bets Today
We’ve highlighted some favorite MLB player prop bets for Cardinals players for Wednesday‘s game, looking at profitable historical betting trends:
- Jose Quintana has hit the Earned Runs Under in 20 of his last 25 games (+14.30 Units / 47% ROI)
- Paul Goldschmidt has hit the RBIs Under in his last 11 away games (+11.00 Units / 50% ROI)
- Paul Goldschmidt has hit the Runs Under in 11 of his last 12 games (+9.80 Units / 56% ROI)
- Tommy Edman has hit the Hits Under in 8 of his last 11 games (+8.40 Units / 62% ROI)
- Tommy Edman has hit the Runs Under in 14 of his last 18 games (+8.05 Units / 29% ROI)
Best Brewers Player Prop Best Bets Today
And here are some favorite MLB player prop bets for Brewers players for Wednesday‘s game, looking at profitable historical betting trends:
- Willy Adames has hit the RBIs Over in 24 of his last 45 games at home (+11.25 Units / 25% ROI)
- Willy Adames has hit the Total Bases Over in 17 of his last 24 games at home (+10.85 Units / 39% ROI)
- Eric Lauer has hit the Strikeouts Under in 16 of his last 21 games (+9.35 Units / 30% ROI)
- Freddy Peralta has hit the Strikeouts Under in his last 9 games (+9.05 Units / 68% ROI)
- Hunter Renfroe has hit the Singles Over in 25 of his last 46 games (+9.05 Units / 19% ROI)
Brewers vs Cardinals Home Run Prop Bets Today
| Over | Under | |
|---|---|---|
| Andrew McCutchen | 0.5 +475 | 0.5 -1000 |
| Christian Yelich | 0.5 +800 | 0.5 -3000 |
| Hunter Renfroe | 0.5 +425 | 0.5 -800 |
| Keston Hiura | 0.5 +750 | 0.5 -3000 |
| Luis Urias | 0.5 +800 | 0.5 -3000 |
Brewers vs Cardinals Total Hits Prop Bets Today
| Over | Under | |
|---|---|---|
| Andrew McCutchen | 0.5 -250 | 0.5 +160 |
| Christian Yelich | 0.5 -165 | 0.5 +115 |
| Hunter Renfroe | 0.5 -200 | 0.5 +145 |
| Keston Hiura | 0.5 -135 | 0.5 -105 |
| Luis Urias | 0.5 -145 | 0.5 +105 |
Brewers vs Cardinals RBI Prop Bets Today
| Over | Under | |
|---|---|---|
| Andrew McCutchen | 0.5 +195 | 0.5 -300 |
| Christian Yelich | 0.5 +250 | 0.5 -400 |
| Hunter Renfroe | 0.5 +145 | 0.5 -200 |
| Keston Hiura | 0.5 +270 | 0.5 -450 |
| Luis Urias | 0.5 +240 | 0.5 -375 |
Brewers vs Cardinals Strikeout Prop Bets Today
| Over | Under | |
|---|---|---|
| Brandon Woodruff | 6.5 -150 | 6.5 +105 |
| Jose Quintana | 5.5 +100 | 5.5 -140 |
Positive Betting Trends for the Cardinals Run Line, Moneyline, Run Totals
- The St. Louis Cardinals have hit the 1st Five Innings (F5) Team Total Under in 10 of their last 12 away games (+8.10 Units / 56% ROI)
Positive Betting Trends for the Brewers: Run Line, Moneyline, Run Totals
- The Milwaukee Brewers have hit the 1st Five Innings (F5) Team Total Under in 4 of their last 6 games (+2.20 Units / 31% ROI)
Cardinals Against the Spread (ATS) Record
Against the spread this MLB season, the Cardinals have gone 85-69 against the Run Line (+10.7 Units / 5.53% ROI).
- 90-65 when betting on the Moneyline for +8.4 Units / 3.77% ROI
- 73-77 when betting on the total runs Over for -12 Units / -7.02% ROI
- 77-73 when betting on the total runs Under for -2.9 Units / -1.7% ROI
Brewers Against the Spread (ATS) Record
Against the spread this MLB season, the Cardinals have gone 65-88 against the Run Line (-30.75 Units / -16.66% ROI).
- 82-72 when betting on the Moneyline for -20.75 Units / -8.52% ROI
- 75-72 when betting on the total runs Over for -3.75 Units / -2.2% ROI
- 72-75 when betting on the total runs Under for -9.25 Units / -5.46% ROI
José Quintana: Cardinals Starting Pitcher Stats & Trends
Jose Quintana has walked 1 of 91 batters (1%) this month (4 games) — best among qualified SPs in MLB; League Avg: 6% — 100th Percentile.
Jose Quintana has a strike rate of just 63% (1,633/2,605) this season — 3rd lowest among qualified SPs in MLB; League Avg: 66% — sixth Percentile.
Jose Quintana has thrown his changeup for a strike just 51% (354/694) of the time since the start of last season — lowest in MLB among starting pitchers with at least 157 total IP; League Avg: 61% — first Percentile.
Jose Quintana has not allowed a HR in any of his last nine starts dating back to August 10th — George Kirby has the longest active streak at 13.
Brandon Woodruff: Brewers Starting Pitcher Stats & Trends
Opponents have a miss rate of 47% (191/408) against Brandon Woodruff on changeups since the start of last season — 2nd best in MLB among starting pitchers with at least 157 total IP; League Avg: 30% — 98th Percentile.
Brandon Woodruff has a strikeout rate of 72% (21 SO in 29 PAs) with two-strikes — best in MLB over the last two weeks; League Avg: 43% — 100th Percentile.
Brandon Woodruff has struck out 34% (90/262) of left-handed batters he faced this season — 2nd best in MLB among starting pitchers with at least 76 total IP; League Avg: 22% — 98th Percentile.
Opponents have a miss rate of 53% (102/191) against Brandon Woodruff on changeups this season — best in MLB among starting pitchers with at least 76 total IP; League Avg: 29% — 100th Percentile.
Cardinals Keys to the Game vs. the Brewers
The Cardinals are 46-10 (.821) when totaling 10 or more hits this season — 6th best in MLB; League Avg: .726.
The Cardinals are 66-3 (.957) when leading entering the 7th inning this season — 3rd best in MLB; League Avg: .882.
The Cardinals are 69-3 (.958) when leading entering the 8th inning this season — 3rd best in MLB; League Avg: .915.
The Cardinals are 15-4 (.789) when tied entering the 8th inning this season — best in MLB; League Avg: .500.
Brewers Keys to the Game vs. the Cardinals
The Brewers are 16-8 (.667) when tied entering the 7th inning this season — tied for 3rd best in MLB; League Avg: .500.
The Brewers are 8-53 (.131) when trailing entering the 7th inning this season — 10th best in MLB; League Avg: .118.
The Brewers are just 9-33 (.214) when allowing 10 or more hits this season — 9th lowest in MLB; League Avg: .274.
The Brewers are just 58-11 (.841) when leading entering the 7th inning this season — 9th lowest in MLB; League Avg: .882.
Cardinals Hitting Stats & Trends
Cardinals hitters have 259 extra-base hits out of 596 total hits (43%) against LHP since the start of last season — best in MLB; League Avg: 35%.
Cardinals hitters have an OPS of .811 (1,345 PA’s) against LHP this season — best in MLB; League Avg: .717.
Cardinals hitters have an OPS of .805 (2,590 PA’s) against LHP since the start of last season — best in MLB; League Avg: .726.
Cardinals hitters are slugging .468 against LHP this season — best in MLB; League Avg: .401.
Brewers Hitting Stats & Trends
The Brewers are batting just .224 against LHP since the start of last season — 2nd lowest in MLB; League Avg: .247.
Brewers hitters are averaging 4.05 pitches per plate appearance against RHP this season — highest in MLB; League Avg: 3.89.
Brewers hitters have an OPS of .750 (4,222 PA’s) against RHP this season — 5th best in MLB; League Avg: .705.
Brewers hitters have chased 20% of pitches out of the zone in non-two strike counts this season — lowest in MLB; League Avg: 24%.
Cardinals Pitching Stats & Trends
Opponents have a miss rate of just 22% against Cardinals pitchers this season — lowest in MLB; League Avg: 26%.
Opponents have a groundball rate of 47% against Cardinals pitchers this season — 2nd highest in MLB; League Avg: 43%.
Opponents have a miss rate of just 23% against Cardinals pitchers since the start of last season — 2nd lowest in MLB; League Avg: 26%.
Opponents have a groundball rate of 46% against Cardinals pitchers since the start of last season — 2nd highest in MLB; League Avg: 43%.
Brewers Pitching Stats & Trends
Brewers pitchers have a strikeout rate of 31% in close and late situations since the start of last season — best in MLB; League Avg: 25%.
Brewers pitchers have a strikeout rate of 32% in close and late situations since the start of 2020 — best in MLB; League Avg: 25%.
Opponents have a miss rate of 28% against Brewers pitchers this season — 4th best in MLB; League Avg: 26%.
Opponents have a groundball rate of 49% against Brewers pitchers this month (25 games) — highest in MLB; League Avg: 43%.
Brewers vs. Cardinals Injuries Tonight That May Affect Prop Bets
- Luis Perdomo (Brewers): Calf, D15
- Alex J Jackson (Brewers): Wrist, D60
- Trevor Rosenthal (Brewers): Hamstring, D15
- Adrian Houser (Brewers): Groin, Day-to-Day
- Miguel Sánchez (Brewers): Elbow, D60
- Jandel Gustave (Brewers): Forearm, D15
- Jonathan Davis (Brewers): Elbow, D10
- Alexander Reyes (Cardinals): Shoulder, D60
- Tyler O’Neill (Cardinals): Hamstring, D10
- Jordan Hicks (Cardinals): Neck, D15
- Drew VerHagen (Cardinals): Hip, D60
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