Giants vs Orioles Prediction, Odds & Player Prop Bets Today – MLB, Sep 18

Baltimore Orioles' Austin Hays swings at a pitch in the third inning of a baseball game between the Baltimore Orioles and the Seattle Mariners, Saturday, June 24, 2023, in Baltimore. The Orioles won 6-4 in 10 innings.
(AP Photo/Julio Cortez)
  • The Orioles are -160 favorites vs the Giants
  • Giants vs Orioles Over / Under today: 8 Runs
  • Giants / Orioles TV Channel: MAS2 | NSBA

The San Francisco Giants (+135) visit Oriole Park at Camden Yards to take on the Baltimore Orioles (-160) on Wednesday, September 18, 2024. First pitch is scheduled for 6:35pm EDT in Baltimore, MD.

This season, the Giants are 73-78 against the spread (ATS), while the Orioles are 80-71 ATS.

Giants vs Orioles Starting Pitchers Today:

  • Giants starting pitcher: Hayden Birdsong 3-5, 4.74 ERA
  • Orioles starting pitcher: Dean Kremer 7-9, 4.07 ERA

Giants vs. Orioles Odds, Run Line, Over/Under & Moneyline

SpreadOver / UnderMoneyline
Giants+1.5 -155O 8 -105+135
Orioles -1.5 +125U 8 -115-160

Giants vs Orioles Prediction for Today’s Game

Based on recent trends the model predicts the Orioles will win Wednesday‘s MLB game with 56.2% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.


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We’ve highlighted some favorite MLB player prop bets for Giants players for Wednesday‘s game, looking at profitable historical betting trends:

Best Giants Player Prop Bets Today:

  • Heliot Ramos has hit the Home Runs Over in 5 of his last 15 away games (+17.45 Units / 116% ROI)
  • Tyler Fitzgerald has hit the Runs Over in 16 of his last 25 away games (+11.40 Units / 44% ROI)
  • Patrick Bailey has hit the Hits Under in 10 of his last 14 away games (+10.50 Units / 75% ROI)
  • Heliot Ramos has hit the Total Bases Over in 14 of his last 20 away games (+9.65 Units / 39% ROI)
  • Patrick Bailey has hit the Hits Runs and RBIs Under in 12 of his last 14 away games (+8.95 Units / 47% ROI)

And here are some favorite MLB player prop bets for Orioles players for Wednesday‘s game, looking at profitable historical betting trends:

Best Orioles Player Prop Best Bets Today:

  • Gunnar Henderson has hit the Home Runs Over in 7 of his last 16 games at home (+25.50 Units / 159% ROI)
  • Colton Cowser has hit the Total Bases Over in 32 of his last 50 games (+12.85 Units / 19% ROI)
  • Adley Rutschman has hit the Runs Under in 18 of his last 22 games (+12.60 Units / 38% ROI)
  • Ryan O’Hearn has hit the Hits Runs and RBIs Under in 17 of his last 22 games (+12.20 Units / 49% ROI)
  • Anthony Santander has hit the RBIs Under in 23 of his last 30 games (+11.30 Units / 21% ROI)
  • The San Francisco Giants have hit the Game Total Over in 42 of their last 73 away games (+12.70 Units / 16% ROI)
  • The San Francisco Giants have hit the Team Total Under in 34 of their last 56 games (+8.39 Units / 13% ROI)
  • The San Francisco Giants have covered the 1st Five Innings (F5) Run Line in 20 of their last 32 away games (+6.40 Units / 16% ROI)
  • The San Francisco Giants have hit the 1st Five Innings (F5) Team Total Under in 12 of their last 18 games (+5.85 Units / 29% ROI)
  • The San Francisco Giants have hit the 1st Five Innings (F5) Moneyline in 15 of their last 30 away games (+5.55 Units / 15% ROI)
  • The Baltimore Orioles have hit the Team Total Under in 49 of their last 76 games (+19.75 Units / 23% ROI)
  • The Baltimore Orioles have covered the Run Line in 76 of their last 142 games (+14.20 Units / 8% ROI)
  • The Baltimore Orioles have hit the Game Total Over in 56 of their last 104 games (+10.25 Units / 9% ROI)
  • The Baltimore Orioles have hit the 1st Five Innings (F5) Team Total Under in 10 of their last 11 games (+9.40 Units / 65% ROI)
  • The Baltimore Orioles have covered the 1st Five Innings (F5) Run Line in 37 of their last 67 games at home (+0.70 Units / 1% ROI)

Giants Against the Spread (ATS) Record

Against the spread this season, the Giants are 74-77 against the Run Line (-9.75 Units / -4.95% ROI).

  • 73-78 when betting on the Moneyline for -15.65 Units / -8.07% ROI
  • 76-69 when betting on the total runs Over for +0.6 Units / 0.36% ROI
  • 69-76 when betting on the total runs Under for -14.8 Units / -8.87% ROI

Orioles Against the Spread (ATS) Record

Against the spread this season, the Orioles are 80-71 against the Run Line (+14.05 Units / 7.73% ROI).

  • 84-67 when betting on the Moneyline for -7.75 Units / -3.53% ROI
  • 79-60 when betting on the total runs Over for +13.6 Units / 8.27% ROI
  • 60-79 when betting on the total runs Under for -27.05 Units / -16.34% ROI

Orioles vs Giants Home Run Prop Bets Today

Over Under
Anthony Santander (BAL) 0.5 +550 0.5 -800
Gunnar Henderson (BAL) 0.5 +575 0.5 -900
Mike Yastrzemski (SF) 0.5 +600 0.5 -900
Michael Conforto (SF) 0.5 +725 0.5 -1200
Heston Kjerstad (BAL) 0.5 +775 0.5 -1200

Orioles vs Giants Total Hits Prop Bets Today

Over Under
Heliot Ramos (SF) 0.5 -250 0.5 +190
Gunnar Henderson (BAL) 0.5 -225 0.5 +175
Tyler Fitzgerald (SF) 0.5 -210 0.5 +160
Emmanuel Rivera (BAL) 0.5 -175 0.5 +135
Patrick Bailey (SF) 0.5 -175 0.5 +135

Orioles vs Giants RBI Prop Bets Today

Over Under
Anthony Santander (BAL) 0.5 +155 0.5 -210
Heston Kjerstad (BAL) 0.5 +175 0.5 -250
Gunnar Henderson (BAL) 0.5 +185 0.5 -250
Adley Rutschman (BAL) 0.5 +190 0.5 -250
Heliot Ramos (SF) 0.5 +190 0.5 -250

Orioles vs Giants Strikeout Prop Bets Today

Over Under
Hayden Birdsong (SF) 4.5 -110 4.5 -120
Dean Kremer (BAL) 6.5 +140 6.5 -185

Hayden Birdsong has walked 6 of 35 batters (17%) this month (2 games) — 4th highest in MLB among starting pitchers with at least 5 total IP; League Avg: 8% — second Percentile.

Hitters have swung at 40% of Hayden Birdsong’s pitches (58/145) this month (2 games) — 3rd lowest in MLB among starting pitchers with at least 5 total IP; League Avg: 48% — first Percentile.

Hayden Birdsong has a strike rate of just 60% (87/145) this month (2 games) — tied for 15th lowest in MLB among starting pitchers with at least 5 total IP; League Avg: 64% — 10th Percentile.

Orioles Starting Pitcher Stats & Trends

Dean Kremer has a first-pitch strike rate of 82% (42/51) in his last two starts — highest in MLB over the last two weeks; League Avg: 65% — 100th Percentile.

Opponents are hitting just .170 (30-for-176) against Dean Kremer when going through the lineup the first time in a game this season — 4th best in MLB among starting pitchers with at least 60 total IP; League Avg: .235 — 97th Percentile.

Opponents are hitting just .132 (15-for-114) against Dean Kremer when facing the leadoff batter in the inning this season — best in MLB among starting pitchers with at least 60 total IP; League Avg: .243 — 100th Percentile.

Dean Kremer had a first-pitch strike rate of 89% (25/28) in his last start — highest in MLB over the last week; League Avg: 65% — 100th Percentile.

Giants Keys to the Game vs. the Orioles

The Giants are 46-30 (.605) after a home loss since the 2023 season — 5th best in MLB; League Avg: .521.

The Giants are just 50-77 (.394) after a road loss since the 2022 season — 5th lowest in MLB; League Avg: .464.

The Giants are 125-4 (.969) when leading entering the 9th inning since the 2023 season — 4th best in MLB; League Avg: .949.

The Giants are just 34-49 (.410) after a road loss since the 2023 season — 5th lowest in MLB; League Avg: .474.

Orioles Keys to the Game vs. the Giants

The Orioles are 21-12 (.636) after a road loss this season — best in MLB; League Avg: .485.

The Orioles are 60-48 (.556) after a loss as underdogs since the 2022 season — best in MLB; League Avg: .415.

The Orioles are 92-30 (.754) when they’ve scored in the first inning since the 2022 season — 2nd best in MLB; League Avg: .639.

The Orioles are 43-19 (.694) vs bottom 10 scoring offenses since the 2023 season — tied for 2nd best in MLB; League Avg: .560.

Giants hitters have 6 extra-base hits out of 9 total hits (67%) against LHP this month (14 games) — best in MLB; League Avg: 34%.

The Giants are batting just .217 with two outs this season — 3rd lowest in MLB; League Avg: .235.

Giants hitters have 1,319 strikeouts in 5,304 PA’s (25%) against LHP since the 2022 season — tied for 3rd highest in MLB; League Avg: 22%.

The Giants are batting just .154 with two-strikes since last season — tied for 3rd lowest in MLB; League Avg: .170.

Orioles hitters have put just 33% of balls in play to the left side of the field this season — lowest in MLB; League Avg: 38%.

Orioles hitters have put just 34% of balls in play to the left side of the field since last season — lowest in MLB; League Avg: 38%.

Orioles hitters have put just 34% of balls in play to the left side of the field with runners in scoring position since the 2022 season — 2nd lowest in MLB; League Avg: 38%.

The Orioles are batting just .137 with runners on base over the last 14 days — lowest in MLB; League Avg: .251.

Opponents have a groundball rate of 49% against Giants pitchers since last season — highest in MLB; League Avg: 43%.

Opponents have a groundball rate of 49% against Giants pitchers since the 2022 season — highest in MLB; League Avg: 43%.

Opponents have a groundball rate of 49% against Giants pitchers this season — highest in MLB; League Avg: 43%.

Giants pitchers have walked 174 of 2,778 batters (6%) when facing the leadoff batter in the inning since last season — 2nd best in MLB; League Avg: 8%.

Opponents have a groundball batting average of just .210 against Orioles pitchers with the shift since last season — best in MLB; League Avg: .244.

Orioles pitchers have walked 290 of 4,242 batters (7%) when facing the leadoff batter in the inning since the 2022 season — tied for 4th best in MLB; League Avg: 8%.

The Orioles have won 41% of road games in which their opponents scored first since last season — highest in MLB; League Avg: 28%.

Orioles pitchers have an ERA of 3.39 (437.2 IP) against division opponents this season — 4th best in MLB; League Avg: 4.07.

Orioles vs. Giants Injuries Tonight That May Affect Prop Bets 

  • Baltimore Orioles – No Injuries Reported
  • San Francisco Giants – No Injuries Reported

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About the Author

Shane Jackson

Read More @Sjacksonmgm

Shane Jackson is a Web Content Writer for BetMGM, covering MLB and NBA. After graduating from the University of Kansas, his previous stops include MLB.com, Lawrence Journal-World, Manhattan Mercury, Bet Chicago Sports, WynnBET, and Sportsbook Review.

Shane Jackson is a Web Content Writer for BetMGM, covering MLB and NBA. After graduating from the University of Kansas, his previous stops include MLB.com, Lawrence Journal-World, Manhattan Mercury, Bet Chicago Sports, WynnBET, and Sportsbook Review.