Giants vs Royals Prediction, Odds & Player Prop Bets Today – MLB, Sep 22

(AP Photo/Colin E. Braley)
  • The Giants are -115 favorites vs the Royals
  • Giants vs Royals Over / Under today: 7 Runs
  • Giants / Royals TV Channel: BSKC | NSBA | ESPN+

The San Francisco Giants (-115) visit Ewing M. Kauffman Stadium to take on the Kansas City Royals (-105) on Sunday, September 22, 2024. First pitch is scheduled for 2:10pm EDT in Kansas City, MO.

This season, the Giants are against the spread (ATS), while the Royals are ATS.

Giants vs Royals Starting Pitchers Today:

  • Giants starting pitcher: Blake Snell 4-3, 3.31 ERA
  • Royals starting pitcher: Seth Lugo 16-8, 3.05 ERA

Giants vs. Royals Odds, Run Line, Over/Under & Moneyline

SpreadOver / UnderMoneyline
Giants-1.5 +155O 7 -115-115
Royals +1.5 -190U 7 -105-105

Giants vs Royals Prediction for Today’s Game

Based on recent trends the model predicts the Giants will win Sunday‘s MLB game with 52.9% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.


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We’ve highlighted some favorite MLB player prop bets for Giants players for Sunday‘s game, looking at profitable historical betting trends:

Best Giants Player Prop Bets Today:

  • Mike Yastrzemski has hit the Home Runs Over in 7 of his last 16 games (+23.50 Units / 147% ROI)
  • Patrick Bailey has hit the Hits Under in 10 of his last 14 away games (+10.65 Units / 76% ROI)
  • Patrick Bailey has hit the Total Bases Under in 11 of his last 14 away games (+10.55 Units / 62% ROI)
  • Tyler Fitzgerald has hit the Runs Over in 15 of his last 25 away games (+9.85 Units / 38% ROI)
  • Grant McCray has hit the Hits Runs and RBIs Under in 9 of his last 10 games (+8.80 Units / 64% ROI)

And here are some favorite MLB player prop bets for Royals players for Sunday‘s game, looking at profitable historical betting trends:

Best Royals Player Prop Best Bets Today:

  • Salvador Perez has hit the Runs Under in 39 of his last 50 games (+21.85 Units / 29% ROI)
  • Bobby Witt Jr. has hit the Home Runs Over in 11 of his last 40 games (+14.55 Units / 36% ROI)
  • Bobby Witt Jr. has hit the Hits Under in 26 of his last 33 games (+13.15 Units / 21% ROI)
  • Tommy Pham has hit the Walks Under in 16 of his last 18 games (+12.10 Units / 30% ROI)
  • Bobby Witt Jr. has hit the Singles Under in 19 of his last 29 games (+12.00 Units / 41% ROI)
  • The San Francisco Giants have hit the Game Total Over in 44 of their last 76 away games (+13.55 Units / 16% ROI)
  • The San Francisco Giants have hit the Team Total Under in 36 of their last 59 games (+9.14 Units / 13% ROI)
  • The San Francisco Giants have covered the 1st Five Innings (F5) Run Line in 22 of their last 35 away games (+7.30 Units / 17% ROI)
  • The San Francisco Giants have hit the 1st Five Innings (F5) Team Total Over in 27 of their last 45 away games (+6.40 Units / 12% ROI)
  • The San Francisco Giants have hit the Moneyline in 14 of their last 24 away games (+6.10 Units / 22% ROI)
  • The Kansas City Royals have covered the Run Line in 43 of their last 77 games at home (+10.24 Units / 11% ROI)
  • The Kansas City Royals have hit the Game Total Under in 14 of their last 19 games (+9.50 Units / 45% ROI)
  • The Kansas City Royals have hit the 1st Five Innings (F5) Team Total Under in 11 of their last 15 games at home (+6.65 Units / 38% ROI)
  • The Kansas City Royals have hit the Moneyline in 45 of their last 77 games at home (+5.85 Units / 6% ROI)
  • The Kansas City Royals have hit the Team Total Under in 9 of their last 12 games at home (+5.70 Units / 41% ROI)

Giants Against the Spread (ATS) Record

Against the spread this season, the Giants are against the Run Line ( Units / ROI).

  • away moneyline record when betting on the Moneyline for ML units Units / ML ROI ROI
  • away total over record when betting on the total runs Over for over units Units / over ROI ROI
  • away total under record when betting on the total runs Under for under units Units / under ROI ROI

Royals Against the Spread (ATS) Record

Against the spread this season, the Royals are against the Run Line ( Units / ROI).

  • home moneyline record when betting on the Moneyline for ML units Units / ML ROI ROI
  • home total over record when betting on the total runs Over for over units Units / over ROI ROI
  • home total under record when betting on the total runs Under for under units Units / under ROI ROI

Royals vs Giants Home Run Prop Bets Today

Over Under
Matt Chapman (SF) 0.5 +425 0.5 -600
Mike Yastrzemski (SF) 0.5 +675 0.5 -1100
Jerar Encarnacion (SF) 0.5 +700 0.5 -1100
Salvador Perez (KC) 0.5 +700 0.5 -1100
Heliot Ramos (SF) 0.5 +700 0.5 -1100

Royals vs Giants Total Hits Prop Bets Today

Over Under
Bobby Witt Jr. (KC) 0.5 -275 0.5 +200
Matt Chapman (SF) 0.5 -250 0.5 +185
Tyler Fitzgerald (SF) 0.5 -200 0.5 +150
Jerar Encarnacion (SF) 0.5 -200 0.5 +150
Salvador Perez (KC) 0.5 -185 0.5 +140

Royals vs Giants RBI Prop Bets Today

Over Under
Matt Chapman (SF) 0.5 +145 0.5 -190
Bobby Witt Jr. (KC) 0.5 +185 0.5 -250
Salvador Perez (KC) 0.5 +185 0.5 -250
Tyler Fitzgerald (SF) 0.5 +190 0.5 -250
Jerar Encarnacion (SF) 0.5 +195 0.5 -275

Royals vs Giants Strikeout Prop Bets Today

Over Under
Blake Snell (SF) 6.5 -120 6.5 -105
Seth Lugo (KC) 5.5 +125 5.5 -160

Opponents have a miss rate of 38% (297/774) against Blake Snell this season — best in MLB among starting pitchers with at least 61 total IP; League Avg: 25% — 100th Percentile.

Opponents are hitting just .180 (178-for-989) against Blake Snell since last season — best in MLB among starting pitchers with at least 126 total IP; League Avg: .247 — 100th Percentile.

Opposing hitters have a miss rate of 44% (68/153) against Blake Snell when he’s behind in the count this season — best in MLB among starting pitchers with at least 61 total IP; League Avg: 23% — 100th Percentile.

Blake Snell has walked 58 of 443 batters (13%) when going through the lineup the second time in a game since last season — 2nd highest in MLB among starting pitchers with at least 126 total IP; League Avg: 7% — first Percentile.

Royals Starting Pitcher Stats & Trends

Seth Lugo has an average spin rate of 3213.5 RPM on curveballs since last season — highest in MLB among starting pitchers with at least 126 total IP; League Avg: 2530.9 — 100th Percentile.

Seth Lugo has thrown breaking pitches 46% of the time (650/1,408) on the first pitch of at-bats since last season — 2nd highest among qualified SPs in MLB; League Avg: 31% — 96th Percentile.

Opponents have a miss rate of just 18% (45/248) against Seth Lugo on the first pitch of at-bats this season — 2nd lowest among qualified SPs in MLB; League Avg: 26% — third Percentile.

Seth Lugo allowed a batting average of .279 vs right-handed batters (10th worst)– ninth Percentile and just .167 vs left-handed batters in the 2022 season (10th best among qualified RPs)– 90th Percentile.

Giants Keys to the Game vs. the Royals

The Giants are just 35-49 (.417) after a road loss since the 2023 season — 5th lowest in MLB; League Avg: .474.

The Giants are 46-30 (.605) after a home loss since the 2023 season — 5th best in MLB; League Avg: .520.

The Giants are 193-6 (.970) when leading entering the 9th inning since the 2022 season — 4th best in MLB; League Avg: .951.

The Giants are 128-4 (.970) when leading entering the 9th inning since the 2023 season — 4th best in MLB; League Avg: .949.

Royals Keys to the Game vs. the Giants

The Royals are just 24-106 (.185) when their opponents score in the first inning since the 2022 season — lowest in MLB; League Avg: .361.

The Royals are just 20-65 (.235) when their opponents score in the first inning since the 2023 season — 2nd lowest in MLB; League Avg: .373.

The Royals are just 67-67 (.500) when they’ve scored in the first inning since the 2022 season — 2nd lowest in MLB; League Avg: .639.

The Royals are just 14-77 (.154) when allowing 2 or more home runs since the 2023 season — lowest in MLB; League Avg: .301.

Giants hitters have 849 strikeouts in 3,392 PA’s (25%) against LHP since last season — 4th highest in MLB; League Avg: 23%.

The Giants are batting just .217 with two outs this season — 3rd lowest in MLB; League Avg: .235.

The Giants are batting just .248 when facing the starting pitcher for the 3rd time in a game since the 2022 season — tied for 3rd lowest in MLB; League Avg: .264.

The Giants are batting just .232 on the road since last season — tied for 3rd lowest in MLB; League Avg: .244.

The Royals won only 28% of their road games in the 2023 season — 2nd lowest in MLB; League Avg: 48%.

Royals hitters have an OBP of just .306 (8,828 PA’s) against RHP since last season — tied for 4th lowest in MLB; League Avg: .316.

Royals hitters are slugging .247 on pitches out of the zone this season — 2nd best in MLB; League Avg: .205.

Royals hitters have just 827 strikeouts in 4,369 PA’s (19%) against RHP this season — 2nd best in MLB; League Avg: 23%.

Opponents have a groundball rate of 49% against Giants pitchers since the 2022 season — highest in MLB; League Avg: 43%.

Opponents have a groundball rate of 49% against Giants pitchers since last season — highest in MLB; League Avg: 43%.

Opponents have a groundball rate of 49% against Giants pitchers this season — highest in MLB; League Avg: 43%.

Giants pitchers have walked 181 of 2,814 batters (6%) when facing the leadoff batter in the inning since last season — 2nd best in MLB; League Avg: 8%.

Royals pitchers have a strikeout rate of just 40% with two-strikes since the 2022 season — 5th lowest in MLB; League Avg: 42%.

Royals pitchers have a strikeout rate of just 21% since the 2022 season — 5th lowest in MLB; League Avg: 23%.

Royals pitchers have a strikeout rate of just 19% in close and late situations this season — lowest in MLB; League Avg: 25%.

The Royals have won 39% of road games in which their opponents scored first this season — highest in MLB; League Avg: 26%.

Royals vs. Giants Injuries Tonight That May Affect Prop Bets 

  • Kansas City Royals – No Injuries Reported
  • San Francisco Giants – No Injuries Reported

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About the Author

Shane Jackson

Read More @Sjacksonmgm

Shane Jackson is a Web Content Writer for BetMGM, covering MLB and NBA. After graduating from the University of Kansas, his previous stops include MLB.com, Lawrence Journal-World, Manhattan Mercury, Bet Chicago Sports, WynnBET, and Sportsbook Review.

Shane Jackson is a Web Content Writer for BetMGM, covering MLB and NBA. After graduating from the University of Kansas, his previous stops include MLB.com, Lawrence Journal-World, Manhattan Mercury, Bet Chicago Sports, WynnBET, and Sportsbook Review.