Guardians vs Cardinals Prediction, Odds & Player Prop Bets Today – MLB, Sep 20

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St. Louis Cardinals' Jordan Walker warms up before a baseball game against the Milwaukee Brewers Thursday, Sept. 28, 2023, in Milwaukee. (AP Photo/Aaron Gash)
(AP Photo/Aaron Gash)
BetMGM Betting @BETMGM Sep 20, 2024, 11:00 AM
  • The Guardians are -110 favorites vs the Cardinals
  • Guardians vs Cardinals Over / Under today: 8 Runs
  • Guardians / Cardinals TV Channel: BSGL | BSMW

The Cleveland Guardians (-105) visit Busch Stadium to take on the St. Louis Cardinals (-115) on Friday, September 20, 2024. First pitch is scheduled for 8:15pm EDT in St. Louis, MO.

This season, the Guardians are 89-65 against the spread (ATS), while the Cardinals are 78-75 ATS.

Guardians vs Cardinals Starting Pitchers Today:

  • Guardians starting pitcher: Ben Lively 12-9, 3.86 ERA
  • Cardinals starting pitcher: Kyle Gibson 8-7, 4.10 ERA

Guardians vs. Cardinals Odds, Run Line, Over/Under & Moneyline

SpreadOver / UnderMoneyline
Guardians-1.5 +155O 8 -105-105
Cardinals +1.5 -190U 8 -115-115

Guardians vs Cardinals Prediction for Today’s Game

Based on recent trends the model predicts the Guardians will win Friday‘s MLB game with 51.6% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.


Bet now on Guardians vs Cardinals and all games with BetMGM


We’ve highlighted some favorite MLB player prop bets for Guardians players for Friday‘s game, looking at profitable historical betting trends:

Best Guardians Player Prop Bets Today:

  • Lane Thomas has hit the Home Runs Over in 5 of his last 16 games (+16.60 Units / 104% ROI)
  • Jose Ramirez has hit the RBIs Under in 19 of his last 22 games (+13.80 Units / 36% ROI)
  • Jose Ramirez has hit the Total Bases Under in 13 of his last 14 away games (+11.75 Units / 60% ROI)
  • Andres Gimenez has hit the Runs Under in 18 of his last 23 away games (+10.10 Units / 25% ROI)
  • Bo Naylor has hit the Hits Runs and RBIs Under in 10 of his last 11 games (+9.90 Units / 76% ROI)

And here are some favorite MLB player prop bets for Cardinals players for Friday‘s game, looking at profitable historical betting trends:

Best Cardinals Player Prop Best Bets Today:

  • Masyn Winn has hit the Home Runs Over in 6 of his last 25 games at home (+30.50 Units / 122% ROI)
  • Nolan Arenado has hit the Total Bases Over in 17 of his last 24 games at home (+12.70 Units / 40% ROI)
  • Jordan Walker has hit the Singles Under in 17 of his last 21 games (+11.45 Units / 39% ROI)
  • Masyn Winn has hit the Hits Over in 19 of his last 25 games at home (+10.20 Units / 19% ROI)
  • Michael Siani has hit the Hits Runs and RBIs Under in 12 of his last 16 games (+9.20 Units / 45% ROI)
  • The Cleveland Guardians have hit the Game Total Under in 42 of their last 71 away games (+15.80 Units / 20% ROI)
  • The Cleveland Guardians have hit the Team Total Under in 29 of their last 42 away games (+14.70 Units / 30% ROI)
  • The Cleveland Guardians have hit the Moneyline in 89 of their last 154 games (+12.82 Units / 6% ROI)
  • The Cleveland Guardians have covered the Run Line in 16 of their last 26 games (+8.05 Units / 25% ROI)
  • The Cleveland Guardians have hit the 1st Five Innings (F5) Team Total Under in their last 7 games (+7.05 Units / 72% ROI)
  • The St. Louis Cardinals have hit the Game Total Under in 16 of their last 24 games at home (+8.20 Units / 31% ROI)
  • The St. Louis Cardinals have hit the 1st Five Innings (F5) Team Total Under in 10 of their last 13 games (+7.05 Units / 44% ROI)
  • The St. Louis Cardinals have hit the Moneyline in 16 of their last 28 games (+5.75 Units / 18% ROI)
  • The St. Louis Cardinals have covered the Run Line in 20 of their last 32 games (+5.70 Units / 12% ROI)

Guardians Against the Spread (ATS) Record

Against the spread this season, the Guardians are 78-76 against the Run Line (+4.45 Units / 2.31% ROI).

  • 89-65 when betting on the Moneyline for +12.82 Units / 6.42% ROI
  • 68-76 when betting on the total runs Over for -16.05 Units / -9.43% ROI
  • 76-68 when betting on the total runs Under for +1.25 Units / 0.74% ROI

Cardinals Against the Spread (ATS) Record

Against the spread this season, the Cardinals are 78-75 against the Run Line (-5.3 Units / -2.54% ROI).

  • 77-76 when betting on the Moneyline for -9.05 Units / -4.93% ROI
  • 70-77 when betting on the total runs Over for -15.27 Units / -9.12% ROI
  • 77-70 when betting on the total runs Under for -0.25 Units / -0.15% ROI

Cardinals vs Guardians Home Run Prop Bets Today

Over Under
Paul Goldschmidt (STL) 0.5 +425 0.5 -600
Jose Ramirez (CLE) 0.5 +500 0.5 -750
Jhonkensy Noel (CLE) 0.5 +525 0.5 -750
Kyle Manzardo (CLE) 0.5 +525 0.5 -750
Jordan Walker (STL) 0.5 +575 0.5 -800

Cardinals vs Guardians Total Hits Prop Bets Today

Over Under
Paul Goldschmidt (STL) 0.5 -250 0.5 +195
Brendan Donovan (STL) 0.5 -250 0.5 +190
Jose Ramirez (CLE) 0.5 -250 0.5 +190
Andres Gimenez (CLE) 0.5 -250 0.5 +175
Nolan Arenado (STL) 0.5 -225 0.5 +165

Cardinals vs Guardians RBI Prop Bets Today

Over Under
Paul Goldschmidt (STL) 0.5 +150 0.5 -200
Josh Naylor (CLE) 0.5 +160 0.5 -210
Jose Ramirez (CLE) 0.5 +165 0.5 -225
Nolan Arenado (STL) 0.5 +170 0.5 -225
Jordan Walker (STL) 0.5 +170 0.5 -225

Cardinals vs Guardians Strikeout Prop Bets Today

Over Under
Kyle Gibson (STL) 4.5 -115 4.5 -110
Ben Lively (CLE) 3.5 +120 3.5 -155

13 of Ben Lively’s 38 breaking pitch strikeouts (34%) have been backdoor this season — 2nd highest in MLB among starting pitchers with at least 61 total IP; League Avg: 14% — 98th Percentile.

Ben Lively has allowed a slugging percentage of .604 (61 Total Bases / 101 ABs) when going through the lineup the third time in a game this season — 2nd highest in MLB among starting pitchers with at least 61 total IP; League Avg: .427 — second Percentile.

Ben Lively has allowed a slugging percentage of .602 (103 Total Bases / 171 ABs) when going through the lineup the third time in a game since last season — highest in MLB among starting pitchers with at least 125 total IP; League Avg: .436 — 0 Percentile.

Ben Lively has averaged 90.1 MPH on fastballs this season — 4th lowest in MLB among starting pitchers with at least 61 total IP; League Avg: 93.6 — third Percentile.

Cardinals Starting Pitcher Stats & Trends

Kyle Gibson has a strike rate of just 55% (335/606) with runners in scoring position this season — lowest among qualified SPs in MLB; League Avg: 64% — second Percentile.

Kyle Gibson has a strike rate of just 60% (1,563/2,611) this season — 2nd lowest among qualified SPs in MLB; League Avg: 65% — third Percentile.

Kyle Gibson has walked 24 of 156 batters (15%) with runners in scoring position this season — highest among qualified SPs in MLB; League Avg: 8% — second Percentile.

Kyle Gibson has thrown his fastball for a strike just 59% (614/1,036) of the time this season — lowest among qualified SPs in MLB; League Avg: 67% — first Percentile.

Guardians Keys to the Game vs. the Cardinals

The Guardians are 24-29 (.453) when allowing 2 or more home runs this season — best in MLB; League Avg: .292.

The Guardians are 29-15 (.659) after a home win this season — 3rd best in MLB; League Avg: .516.

The Guardians are 73-2 (.973) when leading entering the 8th inning this season — best in MLB; League Avg: .900.

The Guardians are 62-8 (.886) when scoring 5 or more runs this season — tied for 2nd best in MLB; League Avg: .803.

Cardinals Keys to the Game vs. the Guardians

The Cardinals are just 24-38 (.387) after a win as favorites since the 2023 season — 3rd lowest in MLB; League Avg: .574.

The Cardinals are 39-20 (.661) when tied entering the 8th inning since the 2022 season — best in MLB; League Avg: .500.

The Cardinals are 21-13 (.618) after a loss as underdogs this season — best in MLB; League Avg: .434.

The Cardinals are 53-56 (.486) after a loss as underdogs since the 2022 season — 5th best in MLB; League Avg: .415.

The Guardians are batting just .296 on the first pitch of at-bats this season — 2nd lowest in MLB; League Avg: .332.

Guardians hitters have put just 35% of balls in play to the left side of the field since the 2022 season — lowest in MLB; League Avg: 38%.

The Guardians have barrels in 4% of PA’s since last season (445/11,778) — lowest in MLB; League Avg: 5%.

Guardians hitters have a Hard-Hit Rate of just 33% on the first pitch of at-bats this season — lowest in MLB; League Avg: 42%.

Cardinals hitters are slugging just .381 against LHP since last season — tied for 3rd lowest in MLB; League Avg: .408.

Cardinals hitters have an OPS of just .660 (1,662 PA’s) against LHP this season — 5th lowest in MLB; League Avg: .711.

The Cardinals are batting just .238 against LHP since last season — tied for 5th lowest in MLB; League Avg: .250.

The Cardinals are batting .249 with two outs since the 2022 season — tied for 2nd best in MLB; League Avg: .236.

Opponents have a groundball batting average of just .206 against Guardians pitchers with runners on base this season — best in MLB; League Avg: .263.

Opponents have a groundball batting average of just .222 against Guardians pitchers this season — best in MLB; League Avg: .249.

The Guardians have allowed 0.86 runs per game (133/154) in late innings this season — best in MLB; League Avg: 1.30.

Guardians pitchers have walked 5 of 161 batters (3%) when facing the leadoff batter in the inning this month (18 games) — best in MLB; League Avg: 8%.

Opponents have a groundball rate of 46% against Cardinals pitchers since the 2022 season — 2nd highest in MLB; League Avg: 43%.

Opponents have a miss rate of just 23% against Cardinals pitchers since the 2022 season — 2nd lowest in MLB; League Avg: 26%.

Opponents have a miss rate of just 23% against Cardinals pitchers since last season — 2nd lowest in MLB; League Avg: 26%.

Cardinals pitchers have a strikeout rate of just 39% with two-strikes since the 2022 season — 3rd lowest in MLB; League Avg: 42%.

Cardinals vs. Guardians Injuries Tonight That May Affect Prop Bets 

  • St. Louis Cardinals – No Injuries Reported
  • Cleveland Guardians – No Injuries Reported

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Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.

Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.