Pirates vs Cardinals Prediction, Odds & Player Prop Bets Today – MLB, Sep 16

St. Louis Cardinals' Jordan Walker warms up before a baseball game against the Milwaukee Brewers Thursday, Sept. 28, 2023, in Milwaukee. (AP Photo/Aaron Gash)
(AP Photo/Aaron Gash)
  • The Pirates are -145 favorites vs the Cardinals
  • Pirates vs Cardinals Over / Under today: 7 Runs
  • Pirates / Cardinals TV Channel: BSMW | SNPT

The Pittsburgh Pirates (-145) visit Busch Stadium to take on the St. Louis Cardinals (+120) on Monday, September 16, 2024. First pitch is scheduled for 7:45pm EDT in St. Louis, MO.

This season, the Pirates are 71-78 against the spread (ATS), while the Cardinals are 75-74 ATS.

Pirates vs Cardinals Starting Pitchers Today:

  • Pirates starting pitcher: Paul Skenes 10-2, 2.10 ERA
  • Cardinals starting pitcher: Andre Pallante 6-8, 4.11 ERA

Pirates vs. Cardinals Odds, Run Line, Over/Under & Moneyline

SpreadOver / UnderMoneyline
Pirates-1.5 +120O 7 -105-145
Cardinals +1.5 -145U 7 -115+120

Pirates vs Cardinals Prediction for Today’s Game

Based on recent trends the model predicts the Pirates will win Monday‘s MLB game with 57.7% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.


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We’ve highlighted some favorite MLB player prop bets for Pirates players for Monday‘s game, looking at profitable historical betting trends:

Best Pirates Player Prop Bets Today:

  • Joey Bart has hit the Home Runs Over in 7 of his last 27 games (+20.50 Units / 76% ROI)
  • Isiah Kiner-Falefa has hit the Total Bases Under in his last 13 away games (+13.85 Units / 65% ROI)
  • Bryan Reynolds has hit the Runs Under in 18 of his last 23 away games (+10.60 Units / 30% ROI)
  • Yasmani Grandal has hit the Walks Over in 6 of his last 7 games (+9.70 Units / 139% ROI)
  • Joey Bart has hit the Hits Runs and RBIs Over in 18 of his last 28 games (+9.45 Units / 31% ROI)

And here are some favorite MLB player prop bets for Cardinals players for Monday‘s game, looking at profitable historical betting trends:

Best Cardinals Player Prop Best Bets Today:

  • Masyn Winn has hit the Home Runs Over in 6 of his last 25 games at home (+30.00 Units / 120% ROI)
  • Paul Goldschmidt has hit the Runs Under in 24 of his last 28 games (+17.20 Units / 36% ROI)
  • Nolan Arenado has hit the Total Bases Over in 15 of his last 20 games at home (+12.25 Units / 46% ROI)
  • Nolan Arenado has hit the Hits Over in 32 of his last 42 games (+11.35 Units / 12% ROI)
  • Jordan Walker has hit the Singles Under in 14 of his last 17 games (+10.05 Units / 42% ROI)
  • The Pittsburgh Pirates have covered the Run Line in 62 of their last 110 games (+11.67 Units / 8% ROI)
  • The Pittsburgh Pirates have hit the Team Total Over in 42 of their last 72 games (+9.75 Units / 12% ROI)
  • The Pittsburgh Pirates have hit the Game Total Over in 27 of their last 46 games (+6.95 Units / 14% ROI)
  • The Pittsburgh Pirates have hit the 1st Five Innings (F5) Team Total Under in 8 of their last 12 away games (+4.25 Units / 33% ROI)
  • The Pittsburgh Pirates have hit the Moneyline in 9 of their last 15 games (+3.08 Units / 16% ROI)
  • The St. Louis Cardinals have hit the Game Total Under in 13 of their last 20 games at home (+6.20 Units / 28% ROI)
  • The St. Louis Cardinals have hit the 1st Five Innings (F5) Team Total Under in 7 of their last 9 games (+5.25 Units / 50% ROI)
  • The St. Louis Cardinals have hit the Moneyline in 13 of their last 24 games (+4.10 Units / 16% ROI)
  • The St. Louis Cardinals have covered the Run Line in 17 of their last 28 games (+3.30 Units / 8% ROI)

Pirates Against the Spread (ATS) Record

Against the spread this season, the Pirates are 80-69 against the Run Line (+6.58 Units / 3.42% ROI).

  • 71-78 when betting on the Moneyline for -8.67 Units / -4.98% ROI
  • 72-72 when betting on the total runs Over for -7.45 Units / -4.5% ROI
  • 72-72 when betting on the total runs Under for -6.22 Units / -3.82% ROI

Cardinals Against the Spread (ATS) Record

Against the spread this season, the Cardinals are 75-74 against the Run Line (-7.7 Units / -3.77% ROI).

  • 74-75 when betting on the Moneyline for -10.7 Units / -6.03% ROI
  • 69-74 when betting on the total runs Over for -12.87 Units / -7.9% ROI
  • 74-69 when betting on the total runs Under for -2.25 Units / -1.38% ROI

Cardinals vs Pirates Home Run Prop Bets Today

Over Under
Andrew McCutchen (PIT) 0.5 +625 0.5 -1000
Paul Goldschmidt (STL) 0.5 +650 0.5 -1000
Oneil Cruz (PIT) 0.5 +675 0.5 -1100
Bryan De La Cruz (PIT) 0.5 +700 0.5 -1100
Bryan Reynolds (PIT) 0.5 +850 0.5 -1600

Cardinals vs Pirates Total Hits Prop Bets Today

Over Under
Nick Gonzales (PIT) 0.5 -250 0.5 +180
Bryan Reynolds (PIT) 0.5 -250 0.5 +195
Masyn Winn (STL) 0.5 -225 0.5 +165
Oneil Cruz (PIT) 0.5 -210 0.5 +160
Bryan De La Cruz (PIT) 0.5 -210 0.5 +155

Cardinals vs Pirates RBI Prop Bets Today

Over Under
Andrew McCutchen (PIT) 0.5 +160 0.5 -210
Oneil Cruz (PIT) 0.5 +175 0.5 -250
Bryan Reynolds (PIT) 0.5 +185 0.5 -250
Rowdy Tellez (PIT) 0.5 +195 0.5 -275
Bryan De La Cruz (PIT) 0.5 +195 0.5 -250

Cardinals vs Pirates Strikeout Prop Bets Today

Over Under
Paul Skenes (PIT) 6.5 -120 6.5 -110
Andre Pallante (STL) 4.5 +115 4.5 -150

Paul Skenes has a strikeout rate of 41% (54 SO in 132 PAs) versus the bottom of the order this season — best in MLB among starting pitchers with at least 59 total IP; League Avg: 24% — 100th Percentile.

Paul Skenes has struck out 50% (11/22) of left-handed batters he faced this month (2 games) — tied for best in MLB among starting pitchers with at least 4 total IP; League Avg: 23% — 100th Percentile.

Paul Skenes has a strikeout rate of 37% (46 SO in 123 PAs) when facing the leadoff batter in the inning this season — best in MLB among starting pitchers with at least 59 total IP; League Avg: 22% — 100th Percentile.

Paul Skenes has a strikeout rate of 32% (151 SO in 468 PAs) this season — 3rd best in MLB among starting pitchers with at least 59 total IP; League Avg: 22% — 98th Percentile.

Cardinals Starting Pitcher Stats & Trends

Left-handed hitters have a groundball rate of 73% (323/440) against Andre Pallante since the 2022 season — highest in MLB among starting pitchers with at least 188 total IP; League Avg: 43% — 100th Percentile.

Opponents have a groundball rate of 68% (128/189) against Andre Pallante in two-strike counts since last season — highest in MLB among starting pitchers with at least 124 total IP; League Avg: 45% — 100th Percentile.

Left-handed hitters have a groundball rate of 76% (214/282) against Andre Pallante since last season — highest in MLB among starting pitchers with at least 124 total IP; League Avg: 42% — 100th Percentile.

Opponents have a groundball rate of 66% (203/309) against Andre Pallante in two-strike counts since the 2022 season — highest in MLB among starting pitchers with at least 188 total IP; League Avg: 45% — 100th Percentile.

Pirates Keys to the Game vs. the Cardinals

The Pirates are just 59-7 (.894) when leading entering the 9th inning this season — 2nd lowest in MLB; League Avg: .948.

The Pirates are just 17-30 (.362) when tied entering the 8th inning since the 2022 season — lowest in MLB; League Avg: .500.

The Pirates are just 6-42 (.125) when allowing 10 or more hits this season — 2nd lowest in MLB; League Avg: .248.

The Pirates are just 37-63 (.370) after a win as underdogs since the 2023 season — tied for 5th lowest in MLB; League Avg: .418.

Cardinals Keys to the Game vs. the Pirates

The Cardinals are just 24-38 (.387) after a win as favorites since the 2023 season — 3rd lowest in MLB; League Avg: .574.

The Cardinals are 21-13 (.618) after a loss as underdogs this season — best in MLB; League Avg: .434.

The Cardinals are 39-19 (.672) when tied entering the 8th inning since the 2022 season — best in MLB; League Avg: .500.

The Cardinals are 43-27 (.614) when tied entering the 7th inning since the 2022 season — 2nd best in MLB; League Avg: .500.

Pirates hitters have an OPS of just .410 (136 PA’s) on the road this month (4 games) — lowest in MLB; League Avg: .682.

Pirates hitters have 447 strikeouts in 1,327 PA’s (34%) in lefty-lefty matchups since the 2022 season — highest in MLB; League Avg: 24%.

The Pirates are batting just .144 on the road this month (4 games) — lowest in MLB; League Avg: .237.

The Pirates are batting just .235 against LHP since the 2022 season — 3rd lowest in MLB; League Avg: .248.

Cardinals hitters have an OBP of just .292 (1,614 PA’s) against LHP this season — 3rd lowest in MLB; League Avg: .313.

The Cardinals are just 44-70 (.373) against the run line (-30.5% ROI) after a road win since the 2022 season — lowest in MLB; League Avg: .495.

The Cardinals are batting just .237 against LHP since last season — tied for 4th lowest in MLB; League Avg: .250.

Cardinals hitters are slugging just .361 against LHP this season — 4th lowest in MLB; League Avg: .397.

Pirates pitchers have 245 three-pitch strikeouts this season — 2nd most in MLB.

Pirates pitchers have walked 1,648 of 18,183 batters (9%) since the 2022 season — 5th highest in MLB; League Avg: 8%.

The Pirates pitchers have allowed their opponents to score first in 54% of their games since last season — 5th highest in MLB; League Avg: 50%.

Opponents have a groundball batting average of .295 against Pirates pitchers with the shift this season — 2nd highest in MLB; League Avg: .249.

Opponents have a groundball rate of 45% against Cardinals pitchers since last season — 2nd highest in MLB; League Avg: 43%.

Opponents have a miss rate of just 23% against Cardinals pitchers since last season — 2nd lowest in MLB; League Avg: 26%.

Opponents have a miss rate of just 23% against Cardinals pitchers since the 2022 season — 2nd lowest in MLB; League Avg: 26%.

Cardinals pitchers have a strikeout rate of just 20% since last season — tied for 2nd lowest in MLB; League Avg: 23%.

Cardinals vs. Pirates Injuries Tonight That May Affect Prop Bets 

  • St. Louis Cardinals – No Injuries Reported
  • Pittsburgh Pirates – No Injuries Reported

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About the Author

Shane Jackson

Read More @Sjacksonmgm

Shane Jackson is a Web Content Writer for BetMGM, covering MLB and NBA. After graduating from the University of Kansas, his previous stops include MLB.com, Lawrence Journal-World, Manhattan Mercury, Bet Chicago Sports, WynnBET, and Sportsbook Review.

Shane Jackson is a Web Content Writer for BetMGM, covering MLB and NBA. After graduating from the University of Kansas, his previous stops include MLB.com, Lawrence Journal-World, Manhattan Mercury, Bet Chicago Sports, WynnBET, and Sportsbook Review.