Bills vs Rams Prediction, Odds & Best Prop Bets โ€“ NFL, Week 14

Los Angeles Rams quarterback Matthew Stafford drops back to pass during an NFL football game against the Seattle Seahawks, Sunday, Sept. 10, 2023, in Seattle. The Rams won 30-13.
(Stephen Brashear/AP Photo)
  • The Bills are -4.5 point favorites vs the Rams
  • Total (Over/Under): 49.5 points
  • Watch this game on FOX

The Buffalo Bills (10-2-0) visit SoFi Stadium to take on the Los Angeles Rams (6-6-0) on Dec. 8. Kickoff is scheduled for 4:25pm EST in Inglewood, CA.

The Bills are betting favorites in this matchup, with the spread sitting at -4.5 (-110).

The Bills vs. Rams Over/Under is 49.5 total points for the game.

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Bills vs. Rams Odds, Spread, Over/Under

SpreadTotal (O/U)Moneyline
Bills-4.5 -11049.5 -110-250
Rams +4.5 -11049.5 -110+200

Bills vs. Rams Prediction

The winning team model predicts the Bills will win this game with 57.0% confidence, based on game simulations, player injuries, offensive & defensive matchups and recent game results.

Bills vs Rams Spread Prediction

Based on recent against-the-spread trends, the model predicts the Rams will cover the spread with 54.0% confidence.

This prediction against the spread factors in ATS performances for both teams, opening and current betting lines plus public and sharp money already wagered on this matchup.


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We’ve highlighted some favorite NFL player prop bets for Bills players this playoff game, looking at profitable historical betting trends:

Best Bills Player Prop Bets Today

  • Khalil Shakir has hit the Receptions Over in 12 of his last 18 games (+6.40 Units / 31% ROI)
  • James Cook has hit the Longest Reception Under in his last 5 games (+5.00 Units / 79% ROI)
  • Amari Cooper has hit the Receptions Under in 6 of his last 7 away games (+4.95 Units / 56% ROI)
  • Mack Hollins has hit the Receptions Under in 7 of his last 9 games (+4.35 Units / 35% ROI)
  • Curtis Samuel has hit the Receptions Under in 9 of his last 14 games (+4.05 Units / 22% ROI)

And here are some top NFL player prop bets for Rams players for this matchup, looking at profitable historical betting trends:

Best Rams Player Prop Best Bets Today

  • Matthew Stafford has hit the Rushing Yards Under in 9 of his last 10 games (+7.80 Units / 50% ROI)
  • Matthew Stafford has hit the Completions Over in 11 of his last 16 games (+5.50 Units / 30% ROI)
  • Kyren Williams has hit the Receiving Yards Under in 11 of his last 16 games (+5.30 Units / 28% ROI)
  • Matthew Stafford has hit the Passing Yards Over in 11 of his last 16 games (+5.20 Units / 28% ROI)
  • Demarcus Robinson has hit the Receptions Under in 11 of his last 15 games (+5.10 Units / 24% ROI)
  • The Buffalo Bills have hit the 2Q Game Total Over in 15 of their last 19 games (+11.60 Units / 52% ROI)
  • The Buffalo Bills have hit the Moneyline in 17 of their last 22 games (+11.55 Units / 20% ROI)
  • The Buffalo Bills have hit the Team Total Over in 14 of their last 21 games (+6.30 Units / 26% ROI)
  • The Buffalo Bills have covered the Spread in 14 of their last 22 games (+5.35 Units / 22% ROI)
  • The Buffalo Bills have hit the 3Q Moneyline in 9 of their last 19 games (+5.15 Units / 16% ROI)
  • The Los Angeles Rams have hit the 3Q Game Total Over in 13 of their last 17 games (+8.40 Units / 40% ROI)
  • The Los Angeles Rams have hit the Moneyline in 12 of their last 20 games (+7.75 Units / 26% ROI)
  • The Los Angeles Rams have hit the 2Q Moneyline in 7 of their last 8 games at home (+6.68 Units / 62% ROI)
  • The Los Angeles Rams have covered the 2Q Spread in 7 of their last 8 games at home (+5.80 Units / 64% ROI)
  • The Los Angeles Rams have hit the 2H Game Total Over in 10 of their last 14 games (+5.46 Units / 36% ROI)

Bills Against the Spread (ATS) Record

Against the spread this NFL season, the Bills art 8-4 (+3.7 Units / 28.03% ROI).

  • Bills are 10-2 when betting on the Moneyline for +8.2 Units / 32.73% ROI
  • Bills are 7-5 when betting the Over for +1.4 Units / 10.53% ROI
  • Bills are 5-7 when betting the Under for -2.7 Units / ROI

Rams Against the Spread (ATS) Record

Against the spread this NFL season, the Rams are 5-7 (-2.65 Units / -20.23% ROI).

  • Rams are 6-6 when betting on the Moneyline for +1.05 Units / 6.29% ROI
  • Rams are 6-6 when betting the Over for -0.65 Units / -4.91% ROI
  • Rams are 6-6 when betting the Under for -0.6 Units / -4.56% ROI

Buffalo Bills: Keys to the Game vs. the Los Angeles Rams

The Bills are 6-0 (1.000) when possessing the ball longer than their opponent this season — T-best in NFL. The Rams has allowed an average time of possession of 31 min and 28 s this season — 5th-highest in NFL.

The Bills are undefeated (7-0) when allowing less than 50% of third down conversion opportunities this season — T-best in NFL; League Avg: .556.

The Bills were 3-1 (.750) when not forcing a turnover last season — T-best in NFL; League Avg: .265.

The Bills are undefeated (4-0) when tied at the end of quarter 1 since the 2023 season — best in NFL; League Avg: .500.

Los Angeles Rams: Keys to the Game vs. the Buffalo Bills

The Rams were undefeated (3-0) when making 3 or more explosive runs in a game last season — T-best in NFL; League Avg: .611.

The Rams are 6-1 (.857) when not losing a fumble this season — T-5th-best in NFL; League Avg: .568.

The Rams were 2-4 (.333) when rushing less than 25 times last season — T-8th-best in NFL; League Avg: .276.

The Rams were 9-4 (.692) when allowing less than 50% of third down conversion opportunities last season — T-9th-best in NFL; League Avg: .570.

Additional Matchup Notes for Buffalo Bills vs. Los Angeles Rams

The Rams have run successful plays on 57.9% of pass attempts on play action passes since the 2023 season — T-2nd-best in NFL. The Bills have allowed successful plays on 54.7% of pass attempts on play action passes since the 2023 season — 4th-worst in NFL.

Rams TEs have just 34.7 receiving yards per game since the 2023 season — 2nd-worst in NFL. The Bills have allowed an average ofjust 43.3 receiving yards per game to TEs since the 2023 season — 5th-best in NFL.

The Bills have scored on 48.8% of their drives this season — 3rd-best in NFL. The Rams defense has allowed scores on 44% of opponent drives this season — 5th-worst in NFL.

The Bills have been successful on 50.6% of plays they have run against a light front this season — best in NFL. The Rams have allowed their opponents to be successful on 44.3% of plays with a light front this season — 4th-worst in NFL.

The Bills have run successful plays on 47.8% of rush attempts with motion this season — 5th-best in NFL. The Rams have allowed successful plays on 49.7% of rush attempts against motion this season — T-4th-worst in NFL.

Buffalo Bills Offense: Important Stats

The Bills ran successful plays on 51% of plays in the 4th quarter last season — best in NFL; League Avg: 40%.

The Bills went three and out on 12% of their drives last season — best in NFL; League Avg: 22%.

The Bills went three and out on 10% of their drives in the 2nd half last season — best in NFL; League Avg: 20%.

The Bills ran successful plays on 50% of plays in the 2nd half last season — best in NFL; League Avg: 41%.

Los Angeles Rams Offense: Important Stats

The Rams have run successful plays on 86% of plays against a light rush this season — best in NFL; League Avg: 42%.

The Rams have run successful plays on 86% of pass attempts against a light rush this season — best in NFL; League Avg: 44%.

The Rams ran successful plays on 70% of rush attempts in Week 13 — best in NFL; League Avg: 44%.

The Rams have targeted WRs 71% of the time (701 Pass Attempts/993 plays) since the 2023 season — highest in NFL; League Avg: 57%.

Buffalo Bills Defense: Important Stats

The Bills defense have allowed -0.80 epa per play with a light rush since the 2023 season — best in NFL; League Avg: -0.02.

The Bills defense has allowed successful plays on 10% of pass attempts with a light rush since the 2023 season — best in NFL; League Avg: 41%.

The Bills defense have allowed -0.21 epa per play with a light front since the 2023 season — best in NFL; League Avg: -0.03.

The Bills defense has allowed a passer rating of just 18.9 with a light rush (19 Pass Attempts) since the 2023 season — best in NFL; League Avg: 85.3.

Los Angeles Rams Defense: Important Stats

The Rams defense has allowed opponents to catch just 52 of 111 passes (47% Reception Pct) on 3rd and long since the 2023 season — best in NFL; League Avg: 62%.

The Rams defense has allowed a passer rating of just 23.2 on 3rd and long (43 Pass Attempts) this season — best in NFL; League Avg: 80.8.

The Rams defense has allowed a Completion Pct of just 43% (52 completions/122 attempts) on 3rd and long since the 2023 season — best in NFL; League Avg: 59%.

The Rams defense has allowed 11 TDs on first drive of the game since the 2023 season — T-most in NFL.

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Our BetMGM editors and authors are sports experts with a wealth of knowledge of the sports industry at all levels. Their coverage includes sports news, previews and predictions, fun facts, and betting.

Our BetMGM editors and authors are sports experts with a wealth of knowledge of the sports industry at all levels. Their coverage includes sports news, previews and predictions, fun facts, and betting.