Bills vs Seahawks Prediction, Odds & Best Prop Bets โ€“ NFL, Week 8

(AP Photo/Abbie Parr)
  • The Bills are -3 point favorites vs the Seahawks
  • Total (Over/Under): 47 points
  • Watch this game on FOX

The Buffalo Bills (5-2-0) visit Lumen Field to take on the Seattle Seahawks (4-3-0) on Oct. 27. Kickoff is scheduled for 4:05pm EDT in Seattle, WA.

The Bills are betting favorites in this matchup, with the spread sitting at -3 (-110).

The Bills vs. Seahawks Over/Under is 47 total points for the game.

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Bills vs. Seahawks Odds, Spread, Over/Under

SpreadTotal (O/U)Moneyline
Bills-3 -11047 -110-160
Seahawks +3 -11047 -110+135

Bills vs. Seahawks Prediction

The winning team model predicts the Bills will win this game with 65.7% confidence, based on game simulations, player injuries, offensive & defensive matchups and recent game results.

Bills vs Seahawks Spread Prediction

Based on recent against-the-spread trends, the model predicts the Bills will cover the spread with 57.8% confidence.

This prediction against the spread factors in ATS performances for both teams, opening and current betting lines plus public and sharp money already wagered on this matchup.


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We’ve highlighted some favorite NFL player prop bets for Bills players this playoff game, looking at profitable historical betting trends:

Best Bills Player Prop Bets Today

  • Khalil Shakir has hit the Receptions Over in 12 of his last 18 games (+6.40 Units / 30% ROI)
  • Curtis Samuel has hit the Receptions Under in 10 of his last 15 games (+5.75 Units / 29% ROI)
  • Khalil Shakir has hit the Receiving Yards Over in 12 of his last 18 games (+5.30 Units / 26% ROI)
  • James Cook has hit the Longest Reception Under in his last 5 games (+5.00 Units / 79% ROI)
  • Ray Davis has hit the Rushing Yards Over in 5 of his last 6 games (+3.70 Units / 53% ROI)

And here are some top NFL player prop bets for Seahawks players for this matchup, looking at profitable historical betting trends:

Best Seahawks Player Prop Best Bets Today

  • Sam Howell has hit the Interceptions Over in 9 of his last 10 games (+7.40 Units / 47% ROI)
  • DK Metcalf has hit the Longest Reception Over in 9 of his last 11 games (+6.70 Units / 52% ROI)
  • Noah Fant has hit the Receptions Over in 7 of his last 8 games at home (+6.50 Units / 65% ROI)
  • Sam Howell has hit the Pass Attempts Under in his last 5 games (+5.00 Units / 79% ROI)
  • Sam Howell has hit the Passing Yards Under in his last 5 games (+5.00 Units / 76% ROI)

First Touchdown Scorer Bet for Seahawks vs Bills

Player Name 1st TD Odds
Kenneth Walker III (Sea) +500
James Cook (Buf) +650
Josh Allen (Buf) +800

Anytime Touchdown Scorer Bet for Seahawks vs Bills

Player Name Anytime TD Odds
Kenneth Walker III (Sea) -140
James Cook (Buf) +110
Josh Allen (Buf) +135
Amari Cooper (BUF) +140
  • The Buffalo Bills have hit the 2Q Game Total Over in 16 of their last 19 games (+13.85 Units / 62% ROI)
  • The Buffalo Bills have hit the 3Q Moneyline in 11 of their last 19 games (+7.15 Units / 23% ROI)
  • The Buffalo Bills have covered the 3Q Spread in 13 of their last 19 games (+6.60 Units / 28% ROI)
  • The Buffalo Bills have hit the 1H Game Total Over in 13 of their last 22 games (+4.90 Units / 20% ROI)
  • The Buffalo Bills have scored last in 4 of their last 5 away games (+2.85 Units / 44% ROI)
  • The Seattle Seahawks have hit the Game Total Over in 8 of their last 10 games at home (+5.80 Units / 53% ROI)
  • The Seattle Seahawks have hit the 3Q Game Total Over in 11 of their last 17 games (+4.25 Units / 22% ROI)
  • The Seattle Seahawks have hit the 2H Moneyline in 4 of their last 5 games at home (+3.10 Units / 43% ROI)
  • The Seattle Seahawks have scored last in 4 of their last 5 games (+3.00 Units / 51% ROI)
  • The Seattle Seahawks have hit the Team Total Over in 6 of their last 9 games at home (+2.85 Units / 27% ROI)

Bills Against the Spread (ATS) Record

Against the spread this NFL season, the Bills art 4-3 (+0.8 Units / 10.53% ROI).

  • Bills are 5-2 when betting on the Moneyline for +3.2 Units / 22.7% ROI
  • Bills are 4-3 when betting the Over for +0.6 Units / 7.69% ROI
  • Bills are 3-4 when betting the Under for -1.4 Units / ROI

Seahawks Against the Spread (ATS) Record

Against the spread this NFL season, the Seahawks are 2-4 (-2.4 Units / -31.17% ROI).

  • Seahawks are 4-3 when betting on the Moneyline for -0.7 Units / -5.6% ROI
  • Seahawks are 5-2 when betting the Over for +2.8 Units / 36.36% ROI
  • Seahawks are 2-5 when betting the Under for -3.5 Units / -45.45% ROI

Buffalo Bills: Keys to the Game vs. the Seattle Seahawks

The Bills are 11-3 (.786) when possessing the ball longer than their opponent since the 2023 season — T-5th-best in NFL. The Seahawks has allowed an average time of possession of 32 min and 27 s since the 2023 season — highest in NFL.

The Bills are 11-3 (.786) when rushing for 120 or more yards since the 2023 season — 8th-best in NFL. The Seahawks have allowed an average of 141.3 rushing yards per game since the 2023 season — 2nd-worst in NFL.

The Bills are 10-1 (.909) at home since the 2023 season — best in NFL; League Avg: .535.

The Bills are 3-1 (.750) after a win this season — T-4th-best in NFL; League Avg: .535.

Seattle Seahawks: Keys to the Game vs. the Buffalo Bills

The Seahawks are undefeated (3-0) when not losing a fumble this season — T-best in NFL; League Avg: .574.

The Seahawks are undefeated (3-0) when not losing a fumble this season — T-best in NFL; League Avg: .574.

The Seahawks were 4-1 (.800) when averaging more than 5 yards per rush last season — T-5th-best in NFL; League Avg: .607.

The Seahawks were 6-4 (.600) when within 7 points at the two minute warning last season — T-9th-best in NFL; League Avg: .500.

Additional Matchup Notes for Buffalo Bills vs. Seattle Seahawks

The Seahawks ran successful plays on just 26.9% of rush attempts last week — 3rd-worst in NFL. The Bills allowed successful plays on just 29.2% of rush attempts last week — 4th-best in NFL.

Seahawks RBs have averaged 7.1 targets per game this season — 3rd-highest in NFL. The Bills have allowed 6.3 receptions per game to RBs this season — 2nd-worst in NFL.

The Bills have a third down conversion rate of 45.6% since the 2023 season — T-2nd-best in NFL. The Seahawks defense has allowed a third down conversion rate of 43.4% since the 2023 season — 2nd-worst in NFL.

The Bills have run 18.2% offensive plays in the red zone this season — 5th-best in NFL. The Seahawks have allowed their opponent to run 18.7% of plays in the red zone this season — 2nd-worst in NFL.

The Bills have run 16.9% offensive plays in the red zone since the 2023 season — 3rd-best in NFL. The Seahawks have allowed their opponent to run 16.1% of plays in the red zone since the 2023 season — 3rd-worst in NFL.

Buffalo Bills Offense: Important Stats

The Bills went three and out on 12% of their drives last season — best in NFL; League Avg: 22%.

The Bills ran successful plays on 51% of plays in the 4th quarter last season — best in NFL; League Avg: 40%.

The Bills have averaged 0.28 epa per play on motion plays this season — best in NFL; League Avg: -0.00.

The Bills ran successful plays on 57% of pass attempts in the 4th quarter last season — best in NFL; League Avg: 43%.

Seattle Seahawks Offense: Important Stats

The Seahawks ran successful plays on 68% of plays against a light rush last season — best in NFL; League Avg: 39%.

The Seahawks averaged 0.63 epa per play against a light rush last season — best in NFL; League Avg: -0.04.

The Seahawks have run 5% of their plays in the red zone in the 1st half this season — worst in NFL; League Avg: 13%.

The Seahawks have averaged 0.43 epa per play against a light rush since the 2023 season — best in NFL; League Avg: -0.03.

Buffalo Bills Defense: Important Stats

The Bills defense have allowed -0.73 epa per play with a light rush since the 2023 season — best in NFL; League Avg: -0.03.

The Bills defense allowed -0.67 epa per play with a light rush last season — best in NFL; League Avg: -0.04.

The Bills defense allowed successful plays on 11% of pass attempts with a light rush last season — best in NFL; League Avg: 40%.

The Bills defense have allowed -1.12 epa per play with tight coverage this season — best in NFL; League Avg: -0.44.

Seattle Seahawks Defense: Important Stats

The Seahawks defense forced three and outs on 7% of opponent drives in the 2nd half last season — worst in NFL; League Avg: 20%.

The Seahawks defense forced three and outs on 2% of opponent drives in the 4th quarter last season — worst in NFL; League Avg: 17%.

The Seahawks defense allowed 3 TD passes in close and late situations last season — T-most in NFL.

The Seahawks defense has allowed 3 TD passes in close and late situations since the 2023 season — T-most in NFL.

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About the Author

Nick Hennion

Read More @nickhennion

Nick Hennion is a senior content writer for BetMGM. His previous stops include VSiN, NBC Sports, The Action Network and Forbes Betting. He owns a bachelor's degree from Syracuse University and a master's degree from Northwestern University.

Nick Hennion is a senior content writer for BetMGM. His previous stops include VSiN, NBC Sports, The Action Network and Forbes Betting. He owns a bachelor's degree from Syracuse University and a master's degree from Northwestern University.