Mariners vs Astros Prediction, Odds & Player Prop Bets Today – MLB, Sep 25

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Houston Astros' Yordan Alvarez runs up the first base line against the Los Angeles Angels during the fourth inning of a baseball game Sunday, June 4, 2023, in Houston.
(AP Photo/David J. Phillip)
BetMGM Betting @BETMGM Sep 25, 2024, 11:02 AM
  • The Mariners are -135 favorites vs the Astros
  • Mariners vs Astros Over / Under today: 7 Runs
  • Mariners / Astros TV Channel: SCHN | RTNW | MLBN

The Seattle Mariners (-135) visit Minute Maid Park to take on the Houston Astros (+115) on Wednesday, September 25, 2024. First pitch is scheduled for 2:10pm EDT in Houston, TX.

This season, the Mariners are 81-77 against the spread (ATS), while the Astros are 79-79 ATS.

Mariners vs Astros Starting Pitchers Today:

  • Mariners starting pitcher: George Kirby 13-11, 3.49 ERA
  • Astros starting pitcher: Yusei Kikuchi 9-9, 4.19 ERA

Mariners vs. Astros Odds, Run Line, Over/Under & Moneyline

SpreadOver / UnderMoneyline
Mariners-1.5 +140O 7 +100-135
Astros +1.5 -165U 7 -120+115

Mariners vs Astros Prediction for Today’s Game

Based on recent trends the model predicts the Mariners will win Wednesday‘s MLB game with 57.2% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.


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We’ve highlighted some favorite MLB player prop bets for Mariners players for Wednesday‘s game, looking at profitable historical betting trends:

Best Mariners Player Prop Bets Today:

  • Luke Raley has hit the Home Runs Over in 10 of his last 32 games (+29.50 Units / 92% ROI)
  • Randy Arozarena has hit the Total Bases Over in 21 of his last 28 games (+12.00 Units / 29% ROI)
  • Justin Turner has hit the Runs Over in 13 of his last 22 games (+11.85 Units / 54% ROI)
  • Julio Rodriguez has hit the Singles Over in 19 of his last 25 away games (+11.70 Units / 36% ROI)
  • Jorge Polanco has hit the Walks Under in 13 of his last 14 games (+11.50 Units / 46% ROI)

And here are some favorite MLB player prop bets for Astros players for Wednesday‘s game, looking at profitable historical betting trends:

Best Astros Player Prop Best Bets Today:

  • Jason Heyward has hit the Home Runs Over in 4 of his last 8 games (+20.10 Units / 251% ROI)
  • Yainer Diaz has hit the Hits Over in 14 of his last 21 games at home (+14.50 Units / 54% ROI)
  • Yainer Diaz has hit the Singles Over in 17 of his last 21 games at home (+11.35 Units / 36% ROI)
  • Yainer Diaz has hit the Hits Runs and RBIs Over in 16 of his last 21 games at home (+10.10 Units / 36% ROI)
  • Yainer Diaz has hit the RBIs Under in 13 of his last 15 games (+9.45 Units / 31% ROI)
  • The Seattle Mariners have hit the Game Total Over in 40 of their last 64 away games (+19.15 Units / 27% ROI)
  • The Seattle Mariners have covered the Run Line in 8 of their last 10 away games (+7.75 Units / 60% ROI)
  • The Seattle Mariners have covered the 1st Five Innings (F5) Run Line in 31 of their last 52 away games (+7.55 Units / 12% ROI)
  • The Seattle Mariners have hit the 1st Five Innings (F5) Team Total Over in 18 of their last 29 games (+5.30 Units / 15% ROI)
  • The Seattle Mariners have hit the Moneyline in 12 of their last 19 games (+3.65 Units / 15% ROI)
  • The Houston Astros have hit the Game Total Under in 81 of their last 141 games (+19.00 Units / 12% ROI)
  • The Houston Astros have covered the Run Line in 56 of their last 100 games (+14.50 Units / 12% ROI)
  • The Houston Astros have hit the Moneyline in 53 of their last 85 games (+10.05 Units / 8% ROI)
  • The Houston Astros have hit the Team Total Over in 35 of their last 58 games at home (+9.40 Units / 14% ROI)
  • The Houston Astros have covered the 1st Five Innings (F5) Run Line in 21 of their last 32 games (+8.10 Units / 20% ROI)

Mariners Against the Spread (ATS) Record

Against the spread this season, the Mariners are 70-88 against the Run Line (-21.8 Units / -10.94% ROI).

  • 81-77 when betting on the Moneyline for -15.95 Units / -7.66% ROI
  • 72-76 when betting on the total runs Over for -10.8 Units / -6.26% ROI
  • 76-72 when betting on the total runs Under for -3 Units / -1.73% ROI

Astros Against the Spread (ATS) Record

Against the spread this season, the Astros are 79-79 against the Run Line (+1.75 Units / 0.91% ROI).

  • 86-72 when betting on the Moneyline for -9.95 Units / -4.26% ROI
  • 64-89 when betting on the total runs Over for -33.25 Units / -19.24% ROI
  • 89-64 when betting on the total runs Under for +18.15 Units / 10.37% ROI

Astros vs Mariners Home Run Prop Bets Today

Over Under
Cal Raleigh (SEA) 0.5 +290 0.5 -375
Kyle Tucker (HOU) 0.5 +400 0.5 -550
Randy Arozarena (SEA) 0.5 +400 0.5 -550
Julio Rodriguez (SEA) 0.5 +475 0.5 -700
Justin Turner (SEA) 0.5 +600 0.5 -900

Astros vs Mariners Total Hits Prop Bets Today

Over Under
Victor Robles (SEA) 0.5 -275 0.5 +195
Julio Rodriguez (SEA) 0.5 -275 0.5 +200
Jose Altuve (HOU) 0.5 -250 0.5 +175
Kyle Tucker (HOU) 0.5 -225 0.5 +165
Alex Bregman (HOU) 0.5 -225 0.5 +170

Astros vs Mariners RBI Prop Bets Today

Over Under
Cal Raleigh (SEA) 0.5 +140 0.5 -185
Alex Bregman (HOU) 0.5 +165 0.5 -225
Yainer Diaz (HOU) 0.5 +175 0.5 -250
Randy Arozarena (SEA) 0.5 +175 0.5 -250
Julio Rodriguez (SEA) 0.5 +175 0.5 -250

Astros vs Mariners Strikeout Prop Bets Today

Over Under
George Kirby (SEA) 4.5 -140 4.5 +105

George Kirby has walked 14 of 565 batters (3%) when going through the lineup the second time in a game since last season — best among qualified SPs in MLB; League Avg: 6% — 100th Percentile.

George Kirby has walked 23 of 781 batters (3%) when going through the lineup the second time in a game since the 2022 season — best among qualified SPs in MLB; League Avg: 7% — 100th Percentile.

George Kirby has walked 28 of 792 batters (4%) when going through the lineup the first time in a game since the 2022 season — best among qualified SPs in MLB; League Avg: 6% — 100th Percentile.

George Kirby has thrown elevated pitches 44% of the time (1,721/3,949) against right-handed batters since the 2022 season — highest among qualified SPs in MLB; League Avg: 25% — 100th Percentile.

Astros Starting Pitcher Stats & Trends

Yusei Kikuchi has thrown his changeup for a strike just 46% (146/317) of the time this season — lowest in MLB among starting pitchers with at least 62 total IP; League Avg: 61% — first Percentile.

Yusei Kikuchi has thrown breaking pitches 48% of the time (254/526) when behind in the count this season — 3rd highest among qualified SPs in MLB; League Avg: 22% — 96th Percentile.

Yusei Kikuchi has allowed a slugging percentage of just .322 (82 Total Bases / 255 ABs) when going through the lineup the second time in a game this season — 8th best among qualified SPs in MLB; League Avg: .383 — 86th Percentile.

Opponents are hitting .276 (71-for-257) against Yusei Kikuchi when going through the lineup the first time in a game this season — tied for 6th highest among qualified SPs in MLB; League Avg: .231 — 12th Percentile.

Mariners Keys to the Game vs. the Astros

The Mariners are 61-7 (.897) when they’ve had 5 or more XBH since the 2022 season — best in MLB; League Avg: .799.

The Mariners are 144-3 (.980) when leading entering the 9th inning since the 2023 season — 2nd best in MLB; League Avg: .949.

The Mariners are 213-4 (.982) when leading entering the 9th inning since the 2022 season — best in MLB; League Avg: .951.

The Mariners are just 62-16 (.795) when leading entering the 7th inning this season — 5th lowest in MLB; League Avg: .856.

Astros Keys to the Game vs. the Mariners

The Astros are just 0-54 (.000) when trailing entering the 9th inning this season — tied for lowest in MLB; League Avg: .050.

The Astros are just 4-10 (.286) after a loss as underdogs this season — 2nd lowest in MLB; League Avg: .434.

The Astros are just 12-23 (.343) when tied entering the 8th inning since the 2023 season — 2nd lowest in MLB; League Avg: .500.

The Astros are 201-30 (.870) when scoring 5 or more runs since the 2022 season — best in MLB; League Avg: .796.

The Mariners are batting just .225 when facing the starting pitcher for the 3rd time in a game since last season — lowest in MLB; League Avg: .264.

The Mariners are batting just .202 when facing the starting pitcher for the 3rd time in a game this season — lowest in MLB; League Avg: .262.

The Mariners are batting just .141 with two-strikes this season — lowest in MLB; League Avg: .168.

Mariners hitters are slugging just .317 when facing the starting pitcher for the 3rd time in a game this season — lowest in MLB; League Avg: .436.

Astros hitters are averaging just 3.64 pitches per plate appearance against RHP this season — lowest in MLB; League Avg: 3.89.

Astros hitters have just 959 strikeouts in 5,296 PA’s (18%) against LHP since the 2022 season — best in MLB; League Avg: 23%.

The Astros are batting .267 against LHP since the 2022 season — 2nd best in MLB; League Avg: .248.

15% of Astros’ hitters plate appearances have lasted only one pitch (918/5,987 PA’s) this season — highest in MLB; League Avg: 12%.

The Mariners pitchers have allowed division opponents to score first in just 25% of their games this season — lowest in MLB; League Avg: 50%.

Mariners pitchers have walked 360 of 5,654 batters (6%) this season — best in MLB; League Avg: 8%.

Mariners pitchers have allowed an OBP of just .276 (5,641 PA’s) this season — best in MLB; League Avg: .312.

Mariners pitchers have walked 74 of 1,404 batters (5%) when facing the leadoff batter in the inning this season — best in MLB; League Avg: 7%.

The average home run distance against the Astros pitchers this season is 388.2 feet — best in MLB; League Avg: 397.6

Opponents have a miss rate of 28% against Astros pitchers since the 2022 season — 2nd best in MLB; League Avg: 26%.

Opponents have a miss rate of 28% against Astros pitchers since last season — 2nd best in MLB; League Avg: 26%.

Opponents have a miss rate of 28% against Astros pitchers this season — 2nd best in MLB; League Avg: 25%.

Astros vs. Mariners Injuries Tonight That May Affect Prop Bets 

  • Houston Astros – No Injuries Reported
  • Seattle Mariners – No Injuries Reported

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Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.

Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.