Cardinals vs Padres Prediction, Odds & Player Prop Bets Today – MLB, Sep 20

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MLB betting odds, predictions and betting odds for today's games
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BetMGM Betting @BETMGM Sep 20, 2022, 3:30 PM
  • The Cardinals (87-61) are -110 favorites vs the Padres (81-66)
  • Cardinals starting pitcher: Adam Wainwright (11-9), 3.28 ERA
  • Padres starting pitcher: Michael Clevinger (5-7), 4.47 ERA
  • Watch the game on TBS

The St. Louis Cardinals (-110) visit PETCO Park to take on the San Diego Padres (-110) on Tuesday, September 20, 2022. First pitch is scheduled for 9:40pm EDT in San Diego.

The Cardinals are betting favorites in this MLB matchup, with the run line sitting at -1.5 (+150).

The Cardinals vs Padres Over/Under is 8 total runs for the game.

So far this season, the Cardinals are 84-61 against the spread (ATS), while the Padres are 64-79 ATS.

Cardinals vs. Padres Odds, Run Line, Over/Under & Moneyline

SpreadOver / UnderMoneyline
Cardinals-1.5 +150O 8 -110-110
Padres +1.5 -185U 8 -110-110

Cardinals vs Padres Prediction for Today’s Game

Based on recent trends the model predicts the will win Tuesday‘s matchup with confidence.

This prediction factors in starting pitchers, recent team and player hitting performances, the last 5 games for both the Cardinals and Padres and up-to-date player injuries.


Looking for a risk-free bet up to $1,000? Bet now on Padres vs Cardinals and all MLB games with BetMGM


Best Cardinals Player Prop Bets Today

We’ve highlighted some favorite MLB player prop bets for Cardinals players for Tuesday‘s game, looking at profitable historical betting trends:

  • Tommy Edman has hit the Hits Over in 16 of his last 19 games (+13.65 Units / 39% ROI)
  • Jose Quintana has hit the Earned Runs Under in 19 of his last 24 games (+13.30 Units / 46% ROI)
  • Tommy Edman has hit the Total Bases Over in 15 of his last 19 games (+12.45 Units / 53% ROI)
  • Corey Dickerson has hit the Total Bases Over in 11 of his last 13 away games (+10.50 Units / 65% ROI)
  • Harrison Bader has hit the Singles Over in 12 of his last 16 away games (+9.10 Units / 57% ROI)

Best Padres Player Prop Best Bets Today

And here are some favorite MLB player prop bets for Padres players for Tuesday‘s game, looking at profitable historical betting trends:

  • Juan Soto has hit the Hits Under in 19 of his last 28 games (+15.90 Units / 54% ROI)
  • Yu Darvish has hit the Pitching Outs Over in 20 of his last 26 games (+13.90 Units / 43% ROI)
  • Josh Bell has hit the Hits Over in 25 of his last 33 games at home (+13.70 Units / 20% ROI)
  • Manny Machado has hit the Singles Under in 23 of his last 32 games at home (+11.65 Units / 29% ROI)
  • Ha-Seong Kim has hit the Runs Under in 16 of his last 18 games at home (+11.40 Units / 32% ROI)

Padres vs Cardinals Home Run Prop Bets Today

Over Under
Austin Nola 0.5 +850 0.5 -5000
Brandon Drury 0.5 +450 0.5 -900
Ha-seong Kim 0.5 +750 0.5 -3000
Jake Cronenworth 0.5 +625 0.5 -1600
Jose Azocar 0.5 +850 0.5 -5000

Padres vs Cardinals Total Hits Prop Bets Today

Over Under
Austin Nola 0.5 -165 0.5 +120
Brandon Drury 0.5 -250 0.5 +170
Ha-seong Kim 0.5 -185 0.5 +125
Jake Cronenworth 0.5 -225 0.5 +160
Jose Azocar 0.5 -175 0.5 +120

Padres vs Cardinals RBI Prop Bets Today

Over Under
Austin Nola 0.5 +220 0.5 -350
Brandon Drury 0.5 +120 0.5 -175
Ha-seong Kim 0.5 +185 0.5 -275
Jake Cronenworth 0.5 +170 0.5 -250
Jose Azocar 0.5 +250 0.5 -400

Padres vs Cardinals Strikeout Prop Bets Today

Over Under
Clevinger 3.5 -110 3.5 -125
Adam Wainwright 3.5 +105 3.5 -150
  • The St. Louis Cardinals have hit the Game Total Under in 5 of their last 6 games (+3.80 Units / 56% ROI)
  • The St. Louis Cardinals have hit the 1st Five Innings (F5) Total Under in 9 of their last 18 games (+2.20 Units / 11% ROI)
  • The San Diego Padres have hit the 1st Five Innings (F5) Total Over in 14 of their last 22 games (+7.70 Units / 32% ROI)
  • The San Diego Padres have hit the Game Total Under in 5 of their last 6 games (+4.05 Units / 64% ROI)
  • The San Diego Padres have covered the 1st Five Innings (F5) Run Line in 7 of their last 10 games (+3.85 Units / 31% ROI)
  • The San Diego Padres have hit the Moneyline in 7 of their last 11 games (+2.80 Units / 19% ROI)
  • The San Diego Padres have hit the 1st Five Innings (F5) Moneyline in 4 of their last 6 games (+1.45 Units / 18% ROI)

Cardinals Against the Spread (ATS) Record

Against the spread this MLB season, the Cardinals have gone 79-66 against the Run Line (+9.4 Units / 5.22% ROI).

  • 84-61 when betting on the Moneyline for +5.7 Units / 2.71% ROI
  • 67-72 when betting on the total runs Over for -12.55 Units / -7.9% ROI
  • 72-67 when betting on the total runs Under for -1.25 Units / -0.79% ROI

Padres Against the Spread (ATS) Record

Against the spread this MLB season, the Cardinals have gone 64-79 against the Run Line (-20.65 Units / -11.62% ROI).

  • 79-65 when betting on the Moneyline for -8.95 Units / -4.21% ROI
  • 69-71 when betting on the total runs Over for -8.35 Units / -5.29% ROI
  • 71-69 when betting on the total runs Under for -4.8 Units / -3.01% ROI

Opponents have a miss rate of just 17% (210/1,244) against Adam Wainwright this season — lowest among qualified SPs in MLB; League Avg: 25% — first Percentile.

Adam Wainwright has thrown breaking pitches 59% of the time (727/1,241) when behind in the count since the start of last season — highest among qualified SPs in MLB; League Avg: 24% — 100th Percentile.

Right-handed hitters have a line drive rate of 31% (93/300) against Adam Wainwright this season — highest among qualified SPs in MLB; League Avg: 23% — second Percentile.

Adam Wainwright has thrown off-speed pitches 66% of the time (390/589) when he’s behind in the count this season — 2nd highest among qualified SPs in MLB; League Avg: 38% — 97th Percentile.

Michael Clevinger: Padres Starting Pitcher Stats & Trends

Mike Clevinger has allowed at least one HR in each of his last five games dating back to August 23rd — Josiah Gray has the longest active streak at 13.

Mike Clevinger has allowed a slugging percentage of .674 (29 Total Bases / 43 ABs) on low fastballs this season — 7th highest in MLB among starting pitchers with at least 72 total IP; League Avg: .431 — sixth Percentile.

Opponents are hitting .205 (41-for-200) against Mike Clevinger with two-strikes this season — 13th highest in MLB among starting pitchers with at least 72 total IP; League Avg: .170 — 10th Percentile.

Mike Clevinger has induced opposing hitters to ground into just 3 double plays in 72 opportunities (4%) this season — tied for 6th lowest in MLB among starting pitchers with at least 72 total IP; League Avg: 11% — fifth Percentile.

Cardinals Keys to the Game vs. the Padres

The Cardinals are 15-9 (.625) when tied entering the 7th inning this season — 6th best in MLB; League Avg: .500.

The Cardinals are 15-4 (.789) when tied entering the 8th inning this season — best in MLB; League Avg: .500.

The Cardinals are 36-34 (.514) on the road this season — tied for 10th best in MLB; League Avg: .472.

The Cardinals are 51-27 (.654) at home this season — 6th best in MLB; League Avg: .528.

Padres Keys to the Game vs. the Cardinals

The Padres are just 3-52 (.055) when trailing entering the 8th inning this season — 5th lowest in MLB; League Avg: .085.

The Padres are 66-21 (.759) when allowing 4 or fewer runs this season — 8th best in MLB; League Avg: .705.

The Padres are 43-35 (.551) on the road this season — 7th best in MLB; League Avg: .472.

The Padres are 20-2 (.909) when totaling 5 or more extra base hits this season — 4th best in MLB; League Avg: .804.

Cardinals hitters have 247 extra-base hits out of 573 total hits (43%) against LHP since the start of last season — best in MLB; League Avg: 35%.

Cardinals hitters have drawn 16 walks in 80 PA’s (20%) against LHP this month (10 games) — best in MLB; League Avg: 8%.

Cardinals hitters have an OPS of 1.066 (80 PA’s) against LHP this month (10 games) — best in MLB; League Avg: .718.

Cardinals hitters are slugging .641 against LHP this month (10 games) — best in MLB; League Avg: .412.

Padres hitters have just 3 strikeouts in 31 PA’s (10%) against LHP over the past seven days (3 games) — best in MLB; League Avg: 23%.

Padres hitters have an OPS of just .676 (2,520 PA’s) at home this season — 5th lowest in MLB; League Avg: .718.

Padres hitters have come to the plate with runners in scoring position in 1,599 of their 4,920 plate appearances (33%) versus relief pitchers since the start of last season — highest in MLB; League Avg: 29%.

Padres hitters are slugging just .382 against LHP since the start of last season — 4th lowest in MLB; League Avg: .408.

Opponents have a groundball rate of 48% against Cardinals pitchers this season — 2nd highest in MLB; League Avg: 43%.

Opponents have a miss rate of just 22% against Cardinals pitchers this season — lowest in MLB; League Avg: 25%.

Cardinals pitchers have a strikeout rate of just 18% with runners in scoring position since the start of last season — tied for lowest in MLB; League Avg: 22%.

Opponents have a miss rate of just 23% against Cardinals pitchers since the start of last season — 2nd lowest in MLB; League Avg: 26%.

Padres pitchers have walked 4 of 194 batters (2%) over the past seven days (6 games) — best in MLB; League Avg: 8%.

Padres pitchers have walked 78 of 1,311 batters (6%) when facing the leadoff batter in the inning this season — 3rd best in MLB; League Avg: 7%.

Opponents have a groundball rate of just 36% against Padres pitchers this month (15 games) — 2nd lowest in MLB; League Avg: 43%.

Opponents have a groundball batting average of just .195 against Padres pitchers with the shift since the start of last season — tied for best in MLB; League Avg: .222.

Padres vs. Cardinals Injuries Tonight That May Affect Prop Bets 

  • Thomas Pomeranz (Padres): Elbow, D60
  • Austin Adams (Padres): Forearm, D60
  • Alexander Reyes (Cardinals): Shoulder, D60
  • Tyler O’Neill (Cardinals): Hamstring, D10
  • Jordan Hicks (Cardinals): Neck, D15
  • Drew VerHagen (Cardinals): Hip, D60

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Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.

Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.