Titans vs Bills Prediction, Odds & Best Prop Bets โ€“ NFL, Week 7

(AP Photo/Joshua Bessex)
  • The Bills are -9 point favorites vs the Titans
  • Total (Over/Under): 41 points
  • Watch this game on CBS

The Tennessee Titans (1-4-0) visit Highmark Stadium to take on the Buffalo Bills (4-2-0) on Oct. 20. Kickoff is scheduled for 1:00pm EDT in Orchard Park, NY.

The Bills are betting favorites in this matchup, with the spread sitting at -9 (-110).

The Titans vs. Bills Over/Under is 41 total points for the game.

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Titans vs. Bills Odds, Spread, Over/Under

SpreadTotal (O/U)Moneyline
Titans+9 -11041 -110+350
Bills -9 -11041 -110-450

Titans vs. Bills Prediction

The winning team model predicts the Bills will win this game with 68.7% confidence, based on game simulations, player injuries, offensive & defensive matchups and recent game results.

Titans vs Bills Spread Prediction

Based on recent against-the-spread trends, the model predicts the Bills will cover the spread with 51.0% confidence.

This prediction against the spread factors in ATS performances for both teams, opening and current betting lines plus public and sharp money already wagered on this matchup.


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We’ve highlighted some favorite NFL player prop bets for Titans players this playoff game, looking at profitable historical betting trends:

Best Titans Player Prop Bets Today

  • Chigoziem Okonkwo has hit the Longest Reception Over in his last 7 games (+7.00 Units / 85% ROI)
  • Will Levis has hit the Completions Under in 10 of his last 14 games (+5.20 Units / 30% ROI)
  • Tyjae Spears has hit the Rushing Yards Under in 11 of his last 16 games (+5.05 Units / 26% ROI)
  • Tony Pollard has hit the Longest Reception Under in 8 of his last 11 games (+4.15 Units / 29% ROI)
  • Nick Folk has hit the Field Goals Under in 11 of his last 16 games (+4.10 Units / 20% ROI)

And here are some top NFL player prop bets for Bills players for this matchup, looking at profitable historical betting trends:

Best Bills Player Prop Best Bets Today

  • Khalil Shakir has hit the Receptions Over in 11 of his last 17 games (+5.15 Units / 26% ROI)
  • James Cook has hit the Longest Reception Under in his last 5 games (+5.00 Units / 79% ROI)
  • Curtis Samuel has hit the Receiving Yards Under in 11 of his last 16 games (+4.60 Units / 22% ROI)
  • Khalil Shakir has hit the Receiving Yards Over in 11 of his last 17 games (+4.30 Units / 22% ROI)
  • Curtis Samuel has hit the Receptions Under in 10 of his last 16 games (+4.15 Units / 20% ROI)

First Touchdown Scorer Bet for Bills vs Titans

Player Name 1st TD Odds
Josh Allen (Buf) +500
James Cook (Buf) +600
Ray Davis (BUF) +650
Tony Pollard (TEN) +750

Anytime Touchdown Scorer Bet for Bills vs Titans

Player Name Anytime TD Odds
Josh Allen (Buf) -120
Tony Pollard (TEN) +120
James Cook (Buf) +120
Ray Davis (BUF) +135

Rushing Props: Total Rushing Yards for Bills vs Titans

Player Name Over Under
Tony Pollard (TEN) 63.5 -115 63.5 -115
Josh Allen (BUF) 30.5 -115 30.5 -115
  • The Tennessee Titans have hit the 1H Moneyline in 13 of their last 19 games (+12.00 Units / 49% ROI)
  • The Tennessee Titans have hit the 2Q Moneyline in 10 of their last 16 games (+6.90 Units / 38% ROI)
  • The Tennessee Titans have covered the 1H Spread in 12 of their last 19 games (+4.10 Units / 19% ROI)
  • The Tennessee Titans have hit the Moneyline in 3 of their last 8 away games (+3.65 Units / 39% ROI)
  • The Tennessee Titans have hit the 1Q Moneyline in 9 of their last 19 games (+3.20 Units / 14% ROI)
  • The Buffalo Bills have hit the 2Q Game Total Over in 15 of their last 19 games (+11.55 Units / 52% ROI)
  • The Buffalo Bills have hit the 3Q Moneyline in 11 of their last 19 games (+7.15 Units / 23% ROI)
  • The Buffalo Bills have covered the 3Q Spread in 13 of their last 19 games (+6.60 Units / 28% ROI)
  • The Buffalo Bills have hit the 1H Game Total Over in 8 of their last 11 games at home (+5.90 Units / 49% ROI)
  • The Buffalo Bills have hit the 2Q Moneyline in 5 of their last 9 games at home (+3.00 Units / 16% ROI)

Titans Against the Spread (ATS) Record

Against the spread this NFL season, the Titans art 1-4 (-3.4 Units / -62.96% ROI).

  • Titans are 1-4 when betting on the Moneyline for -3.6 Units / -60.5% ROI
  • Titans are 2-2 when betting the Over for -0.2 Units / -3.64% ROI
  • Titans are 2-2 when betting the Under for -0.2 Units / ROI

Bills Against the Spread (ATS) Record

Against the spread this NFL season, the Bills are 3-3 (-0.2 Units / -3.08% ROI).

  • Bills are 4-2 when betting on the Moneyline for +2.2 Units / 23.66% ROI
  • Bills are 3-3 when betting the Over for -0.4 Units / -5.97% ROI
  • Bills are 3-3 when betting the Under for -0.3 Units / -4.62% ROI

Tennessee Titans: Keys to the Game vs. the Buffalo Bills

The Titans were 1-2 (.333) when forcing 2 or more turnovers last season — T-2nd-worst in NFL; League Avg: .707.

The Titans are 1-9 (.100) when converting less than 55% of its red zone chances into touchdowns since the 2023 season — T-worst in NFL; League Avg: .462.

The Titans were winless (0-5) after a win last season — T-worst in NFL; League Avg: .496.

The Titans are 1-14 (.067) when scoring less than 22 points since the 2023 season — 3rd-worst in NFL; League Avg: .251.

Buffalo Bills: Keys to the Game vs. the Tennessee Titans

The Bills were 3-1 (.750) when not forcing a turnover last season — T-best in NFL; League Avg: .265.

The Bills are 3-1 (.750) when not forcing a turnover since the 2023 season — T-best in NFL; League Avg: .261.

The Bills are undefeated (3-0) when tied at the end of quarter 1 since the 2023 season — best in NFL; League Avg: .500.

The Bills were winless (0-4) when rushing less than 25 times last season — T-worst in NFL; League Avg: .276.

Tennessee Titans Offense: Important Stats

The Titans have run 27% of their plays in their opponent’s territory in the 4th quarter this season — worst in NFL; League Avg: 52%.

The Titans have run 34% of their plays in their opponent’s territory in the 2nd half this season — worst in NFL; League Avg: 49%.

The Titans allowed a QB hit on 29% of pass attempts last season — worst in NFL; League Avg: 17%.

The Titans ran successful plays on 20% of pass attempts against a base rush in Week 6 — worst in NFL; League Avg: 48%.

Buffalo Bills Offense: Important Stats

The Bills ran successful plays on 51% of plays in the 4th quarter last season — best in NFL; League Avg: 40%.

The Bills have averaged 0.53 epa per play against a light front this season — best in NFL; League Avg: -0.01.

The Bills ran successful plays on 57% of pass attempts in the 4th quarter last season — best in NFL; League Avg: 43%.

The Bills ran successful plays on 50% of plays in the 2nd half last season — best in NFL; League Avg: 41%.

Tennessee Titans Defense: Important Stats

The Titans defense has allowed successful plays on 17% of pass attempts against play action passes this season — best in NFL; League Avg: 51%.

The Titans defense has allowed a passer rating of just 38.4 against play action passes (29 Pass Attempts) this season — best in NFL; League Avg: 101.1.

The Titans defense allowed 9 rushing TDs on 89 carries (9.9 Carries Per TD) in the red zone last season — best Carries Per TD rate in NFL; League Avg: 5.6.

The Titans defense has allowed first downs on 20% of rush attempts in the red zone since the 2023 season — best in NFL; League Avg: 31%.

Buffalo Bills Defense: Important Stats

The Bills defense have allowed -0.70 epa per play with a light rush since the 2023 season — best in NFL; League Avg: -0.02.

The Bills defense allowed successful plays on 11% of plays with a light rush last season — 2nd-best in NFL; League Avg: 39%.

The Bills defense allowed successful plays on 11% of pass attempts with a light rush last season — best in NFL; League Avg: 40%.

The Bills defense allowed -0.67 epa per play with a light rush last season — best in NFL; League Avg: -0.04.

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Our BetMGM editors and authors are sports experts with a wealth of knowledge of the sports industry at all levels. Their coverage includes sports news, previews and predictions, fun facts, and betting.

Our BetMGM editors and authors are sports experts with a wealth of knowledge of the sports industry at all levels. Their coverage includes sports news, previews and predictions, fun facts, and betting.