Baltimore Orioles 2025 Preview: MLB Odds & Prediction

The Baltimore Orioles are still looking for their first playoff win since 2014 following a second straight one-and-done appearance in the postseason.

• 2024: Lost 2-0 to the Kansas City Royals in the American League wild card
• 2023: Lost 3-0 to the Texas Rangers in the ALDS

Can Baltimore’s promising young roster take the next step?

Here’s a look at the updated MLB betting market and my prediction for the Orioles ahead of the 2025 season:

Orioles MLB Odds 2025

Win Total: 89.5
AL East: +240
AL Pennant: +550
World Series: +1500

The market has similar expectations for the Orioles’ MLB odds, following last year’s 91-71 finish, which placed them second in the AL East.

Baltimore’s win total dropped one game compared to last season, while its AL East odds have gone from +180 to +240 since last spring. The Orioles’ World Series odds and pennant price tag have remained the same, suggesting bettors still believe in their potential.

For comparison, here is a look at Baltimore’s preseason odds in recent years:

Orioles Depth Chart 2025

According to RosterResource, the Orioles project to have a similar depth chart to last year’s team. 

The most significant exception is that Corbin Burnes is no longer the ace of Baltimore’s rotation after signing a six-year, $210 million contract with the Arizona Diamondbacks. 

Outfielder Anthony Santander also left the team this offseason, inking a five-year, $92.5 million deal with Toronto Blue Jays.

Projected lineup

Projected rotation

Orioles Player to Watch in 2025

Jackson Holliday enters the 2025 MLB as the most intriguing player on Baltimore’s roster.

Holliday, the son of seven-time All-Star Matt Holliday, was considered the best prospect in baseball this time last year. Jackson Holliday then had an underwhelming rookie season after making his MLB debut on April 10, posting an OPS+ of 66.

It’s not a given that Holliday will become Baltimore’s everyday second baseman, but I’m not ready to give up a player with this kind of upside.

A breakout season from Holliday could provide a massive boost to an Orioles’ offense that faded down the stretch, scoring one total run in the AL wild card last October.

Holliday is featured in a unique futures market at BetMGM, regarding which Jackson will hit the most home runs in 2025:

• Jackson Chourio -120
• Jackson Merrill +135
• Jackson Holliday +500

Orioles 2025 Betting Prediction

Based on the updated MLB betting market, my prediction for the Orioles in 2025 is over on 89.5 wins (-105) after they have cleared this total in back-to-back seasons.

Baltimore remains the biggest threat to the New York Yankees in the AL East, so I don’t mind taking a look at their discounted division odds. However, if Baltimore continues to be quiet in free agency, the price may get better.

The Orioles didn’t trade for Burnes until February of last year, so there is still a chance they make a move before opening day. They need an ace after losing Burnes, but the rotation remains solid, and a big year from Grayson Rodriguez could help fill the void.

More importantly, the lineup has plenty of depth in a league where most teams have question marks in the bottom third of the order. Gunnar Henderson is coming off a third-place finish in the AL MVP race, while Colton Cowser and Jordan Westburg flashed their potential last season.

I’m also buying any stock you want to sell on Adley Rutschman and Holliday. And don’t forget that the left-field wall is moving closer to home plate. RIP the “not in Baltimore” posts.

This is the perfect time to bet on the Orioles after consecutive postseason disappointments.

Prediction: Over 89.5 wins (-105)

2025 MLB Team Previews & Predictions